SAFETY, TOLERABILITY, AND PHARMACOKINETIC INTERACTIONS OF ATAZANAVIR AND RIFAMP

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项研究是为了找出用于治疗艾滋病毒的药物阿扎那韦和用于治疗肺部感染结核病(TB)的药物利福平在同时服用这些药物的人的血液中的水平。这将通过在参与者服药后的不同时间测量参与者血液中的这些药物来完成。这项研究还将检查同时服用这些药物的安全性，并观察它们的耐受性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is being done to find out the levels of atazanavir, a drug used to treat HIV, and rifampin, a drug used to treat the lung infection tuberculosis (TB), are processed in the blood of persons who take these drugs at the same time. This will be done by measuring these drugs in the participants blood at different times after the participant's take the drugs. This study will also examine the safety of these drugs when taken at the same time and see how well they are tolerated.