Clinical Research Enhancement from Supplemental Training

说明.说明申请的广泛、长期目标和具体目标，并提及 项目简要描述研究设计和实现这些目标的方法。避免总结过去的成就， 使用第一人称。本说明书旨在作为建议工作的简洁和准确的说明， 应用程序.如果申请获得资助，此描述将成为公共信息。因此不包括 专有/机密信息。不要超过所提供的空间。 这项建议要求临床研究课程奖继续和扩大该计划 通过补充培训（CREST）加强临床研究， 加州，圣地亚哥。该奖项将使UCSD继续提供全面的， 为未来的临床和转化研究领导者提供研究方法的多学科培训。 CREST的主要目标是为学者提供a）以患者为导向的坚实基础 包括临床试验、流行病学、生物统计学和结果研究的研究方法，B 研究资源，指导和指导，以及c）沟通，赠款写作的实用技能 职业生涯管理和跨学科合作。通过学习设计、管理、分析和 发表重要的临床研究，鼓励学者成为独立的研究者。 该计划是针对临床导向的医学博士，药学博士，或博士谁是在奖学金培训 或在初级教师职位，但也接受护士和其他卫生专业人员与先进的 度为招聘少数民族和女性申请人作出了特别努力。课程工作包括 计算机和基于问题的学习，并在八个季度内以模块化格式提供， 夜校每周一次，从而使学者保持他们的主要研究，临床，或 其他职业活动。学者与CREST顾问相匹配，为职业生涯提供指导 发展。临床研究高级研究硕士学位课程，由 Ithe CREST教师提供与每个学者的需求相关的研究方法的高级培训， linintersts。 I在下一个资助期内，我们建议通过实施一项新的 专业发展模块，增强指导经验，创建培训 为医学生和住院医师提供机会，并开发基于网络的远程 Ilearning模块进一步将CREST模块转换为时间和距离无关的指令。 我们的目标是确保从这个计划中脱颖而出的学者将拥有基本的技能 独立临床研究的必要性。 履约地点（组织、城市、州） 加州大学圣地亚哥分校医学院，加利福尼亚州拉霍亚 加州大学圣地亚哥分校医学中心，加州大学，圣地亚哥，加利福尼亚州 加州大学圣地亚哥分校桑顿医院，加州大学，加利福尼亚州，拉霍亚 圣地亚哥退伍军人医疗中心，加利福尼亚州，拉霍亚 关键人员。参见第11页的说明。使用延续 名称机构 Ravindra L Mehta MD UCSD J.艾伦麦卡琴医学博士加州大学圣地亚哥分校 Gerry Boss MD UCSD W. Chris马修斯医学博士，MSPH UCSD 西奥多Ganiats MD UCSD Deborah Wingard博士UCSD 丹尼尔Masys医学博士，加州大学圣地亚哥分校 Michael齐格勒，加州大学圣地亚哥分校医学博士 提供所需信息的格式 在项目中的作用 项目主任 副主任，研究领域协调员 副主任，研究领域协调员 研究领域协调员 研究领域协调员 研究领域协调员 研究领域协调员 GCRC主任 PHS 398（修订版5/95）第2页 在整个应用程序的底部连续编号页面。不要使用后缀，如3a，3b 主要研究者/PrDogireacmt（oLrasFt，irstM，iddle）M：ehtRa，avindLrall 主要估算者/产品开发人员的一部分提供了地形特征，可持续变化。 研究资助

DESCRIPTION. State the application's broad, long-term objectives and specific aims, making reference to the health relatedness of the project. Describe concisely the research design and methods for achieving these goals. Avoid summaries of past accomplishments and the use of the first person. This description is meant to serve as a succinct and accurate description of the proposed work when separated from the application. If the application is funded, this description, as is, will become public information. Therefore, do not include proprietary/confidential information. DO NOT EXCEED THE SPACE PROVIDED. This proposal requests a Clinical Research Curriculum Award to continue and expand the program for Clinical Research Enhancement through Supplemental Training (CREST) at the University of California, San Diego. This award will allow UCSD to continue to provide comprehensive, multidisciplinary training in research methods for future leaders in clinical and translational research. CREST has the primary objective of providing scholars with a) a solid foundation in patient-oriented research methodology covering clinical trials, epidemiology, biostatistics, and outcomes research, b research resources, mentorship and guidance, and c) practical skills in communications, grant writing career management, and interdisciplinary collaboration. By learning to design, manage, analyze and publish important clinical studies Scholars are encouraged to become independent investigators. The program is targeted to clinically-oriented MDs, PharmDs, or PhDs who are in fellowship training or in junior faculty positions, but also accepts nurses and other health professionals with advanced degrees. Special efforts are made to recruit minority and female applicants. The course work includes computer- and problem-based learning and is delivered in a modular format over eight quarters in evening classes once a week, thereby allowing scholars to maintain their primary research, clinical, or other occupational activities. Scholars are matched to a CREST Advisor to provide guidance for career Idevelopment. A degree program for a Master of Advanced Studies in Clinical Research developed by Ithe CREST faculty offers advanced training in research methods relevant to each Scholar's needs and linterests. I During the next grant period, we propose to enhance the program by implementing a new IProfessional development module, augmenting the mentoring experience, creating training Iopportunities for medical students and resident physicians, and developing a web-based distance Ilearning module to further transform CREST modules into time- and distance-independent instruction. IOur goal is to ensure that scholars emerging from this program will have the fundamental skills Inecessary for independent clinical research. PERFORMANCE SITE(S) (organization, city, state) UCSD School of Medicine, University of California, San Diego, La Jolla, CA UCSD Medical Center, University of California, San Diego, San Diego CA UCSD Thornton Hospital, University of California, San Diego, La Jolla, CA San Diego Veterans Medical Center, La Jolla, CA KEY PERSONNEL. See instructions on Page 11. Use continuation Name Organization Ravindra L Mehta MD UCSD J. Allen McCutchan MD UCSD Gerry Boss MD UCSD W. Chris Mathews MD, MSPH UCSD Theodore Ganiats MD UCSD Deborah Wingard PhD UCSD Daniel Masys MD, UCSD Michael Ziegler MD UCSD pages as needed to provide the required information in the format Role on Project Program Director Associate Director, Research Area Coordinator Associate Director, Research Area Coordinator Research Area Coordinator Research Area Coordinator Research Area Coordinator Research Area Coordinator Director, GCRC PHS 398 (Rev 5/95) Page 2 Number pagesconsecutively at the bottom throughoutthe application. Do not use suffixes such as 3a, 3b PrincipInavl estigator/PrDogireacmt(oLrasFt,irstM, iddle)M: ehtRa,avindLrall Thenamoeftheprincipinavl estigator/prdoigreracmtmorusbteprovidaetdthetopofeacphrintepdagaendeacchontinuaptioange. RESEARCH GRANT