3T MR imaging/spectrometer for heart and brain research

描述(由申请人提供)： 南加州大学(USC)迫切需要一个致力于研究的3T全身磁共振成像/光谱分析平台。南加州大学凯克医学院院长(Stephen Ryan，MD)和该大学校长(Stephen Sample，PhD)表示支持在健康科学校园建设最先进的磁共振成像中心，这进一步加强了这一点。这个平台的跨学科性质，以及它为广泛研究带来的优势和能力，代表了南加州大学在未来十年统一心血管和神经科学研究的主题。这项提议得到了众议院耳朵研究所、帕萨迪纳亨廷顿纪念医院、洛杉矶儿童医院以及南加州大学公园和健康科学校园的研究人员的支持。这些机构/地点都没有一个专门的研究平台，具有我们所要求的能力，所有这些研究人员都对这种仪器将使之成为可能的实验非常热情。南加州大学在核磁共振成像和光谱学方面拥有大量的技术专长，研究人员来自放射学、神经学和生物医学工程。此外，在心血管医学和电气工程领域有高场磁共振系统的经验。这一最先进的系统将提供心血管和神经科学尖端研究所需的超高速成像、卓越的光谱定位和扩散能力；这些能力对于该机构目前正在进行的许多NIH资助的项目至关重要。此外，它将为目前正在审查的众多赠款提供一个理想的实验平台。

DESCRIPTION (provided by applicant): There is a critical need for a 3T whole body MR imaging/spectrometry platform dedicated to research at the University of Southern California (USC). This was reinforced by the Dean (Stephen Ryan, MD) at the Keck School of Medicine at USC, and the president of the University (Stephen Sample, PhD) who have stated their support for the construction of a state of the art magnetic resonance imaging center to be located on the Health Sciences Campus. The interdisciplinary nature of this platform, with the advantages and capabilities it brings to a wide range of studies, typifies the theme of unifying research in both cardiovascular and neurological sciences at USC in the coming decade. This proposal has support from investigators at the House Ear Institute, Huntington Memorial Hospital of Pasadena, Children's Hospital of Los Angeles, and both the University Park and Health Sciences Campus at USC. None of these institutions/locations has a dedicated research platform that has the capabilities that we are requesting, and all of these researchers are extremely enthusiastic about the experiments that this instrumentation will make possible. There is a substantial amount of technical expertise with MR imaging and spectroscopy at USC, with investigators from Radiology, Neurology, and Biomedical Engineering. In addition, experience with high field MR systems is present in Cardiovascular Medicine, and Electrical Engineering. This state-of-the-art system will provide ultra high speed imaging, superb spectral localization, and diffusion capabilities which are required by the cutting edge research in both cardiovascular and neurological sciences; these capabilities are critical for a number of NIH funded projects that are currently underway at this institution. Moreover, it will provide an ideal experimental platform for numerous grants that are currently under review.