Florida Node of The Drug Abuse Clinical Trials Network

描述（由申请人提供）： 这是NIDA CTN佛罗里达节点的竞争延续提案。该节点的目的是制定和执行协议，在各种不同的患者群体的社区治疗环境中测试治疗的有效性，并以改善节点、波多黎各和全国药物滥用治疗实践的方式传播知识。由这笔赠款资助的伙伴关系由迈阿密大学家庭研究中心领导，其相当多的临床试验，多地点，艾滋病毒+，种族/民族和药物滥用治疗专业知识，作为区域研究和培训中心（RRTC）。佛罗里达节点管理代表了RRTC和CTP之间强大的双向协作。这一伙伴关系的合作者是五个佛罗里达现金转拨方案，它们是该州最大和最受尊敬的现金转拨方案之一，代表该州的北部（杰克逊维尔的网关）、西部（坦帕/圣彼得堡的PAR）、东部（奥兰多的无毒品生活中心）和南部（迈阿密的村庄;布劳沃德县的频谱）。占佛罗里达药物滥用治疗资金的45%，并有能力为20，000名患者提供服务，这些机构提供了特殊的治疗方式，患者种族和民族概况以及药物滥用和成瘾人群的多样性。该节点还包括与佛罗里达单一州机构主任、佛罗里达ATTC和佛罗里达供应商协会的强大合作关系。正如我们的进度报告所显示的那样，过去四年来，我们与这些伙伴的合作取得了重大成就。 此外，该提案提出了一些辅助关系，以扩大治疗环境的多样性，包括初级保健和社会服务环境，其代表是两个基于迈阿密-戴德县的大型初级保健网络、一个美沙酮治疗网络、一个政府运营的药物滥用治疗网络、与波多黎各和维尔京群岛ATTC的密切合作以及波多黎各的一个提供者网络等。 我们在过去4年中建立的基础设施使我们能够应对我们最初面临的挑战（例如，我们的团队通过跨地理距离的沟通和协作，成功实施了六项CTN方案，包括领导一项针对药物滥用青少年的家庭治疗大型试验（CTN-0014），以及共同领导首个针对西班牙语人群的药物滥用治疗多中心有效性试验（CTN-0021）。一个非常适合CTN的概念，提出了在传播有效的艾滋病毒干预措施方面测试两种战略。

DESCRIPTION (provided by applicant): This is a competing continuation proposal for the Florida Node of NIDA's CTN. The aim of the Node is to develop and implement protocols that test the effectiveness of treatments across a broad range of community-based treatment settings with diverse patient populations, and to disseminate knowledge in a manner that improves the practice of drug abuse treatment in the Node, Puerto Rico and the nation. The partnership funded by this grant is led by the University of Miami-Center for Family Studies, with its considerable clinical trials, multi-site, HIV+, race/ethnicity, and drug abuse treatment expertise, serving as the Regional Research and Training Center (RRTC). The Florida Node governance represents strong bi-directional collaboration between the RRTC and CTPs. Collaborators in this partnership are five Florida CTPs that are among the largest and most respected in the State, representing the north (Gateway in Jacksonville), west (PAR in the Tampa/St Petersburg), East (Center for Drug Free Living in Orlando) and south (The Village in Miami; Spectrum in Broward County) parts of the State. Accounting for 45% of Florida's drug abuse treatment dollars, and with the capacity to serve 20,000 patients, these agencies offer exceptional diversity of treatment modalities, patient racial and ethnic profiles, and drug abusing and addicted populations. The Node also includes strong collaborative relationships with the Florida Single State Agency Director, the Florida ATTC, and the Florida provider association. As our progress report shows, the past 4 years have yielded major accomplishments in our work with these partners. Additionally, this proposal presents a number of ancillary relationships to expand the diversity of treatment settings, including primary care and social service settings represented by two large Miami-Dade County based primary care networks, a methadone treatment network, a government-run drug abuse treatment network, a close collaboration with the Puerto Rico and Virgin Islands ATTC, and a network of providers in Puerto Rico, among others. The infrastructure we have established over the past 4 years have allowed us to meet the challenges we had originally confronted (e.g., communication and collaboration across geographic distance) and have allowed us to successfully implement six CTN protocols including leading a large trial of family therapy for substance abusing adolescents, (CTN-0014), and co-leading the first ever multi-site effectiveness trial of drug abuse treatment with a Spanish-speaking population (CTN-0021). A concept, ideally suited for the CTN, proposes to test two strategies in the dissemination of an efficacious HIV intervention.