Resonantly enhanced fluorescence spectroscopy of industrial process liquids.

该项目将探索使用光学方法，如共振增强荧光进行细菌鉴定。我们将在之前的项目中与宝洁公司共同开发的光子传感器能力的基础上，对仪器进行相应的调整。试点结果已经表明，我们的导模共振（GMR）传感器模式可以共振增强荧光发射。我们将以这些结果为基础，利用它们更详细地研究形成生物膜的细菌；我们的目标是区分革兰氏阳性和革兰氏阴性细菌作为第一步。更详细地确定细菌种类，从而确定工艺流体中的污染源，更具挑战性，但却是可行的。除了提供有关细菌污染的更好信息外，该技术还可能能够识别工艺液体的化学混合物，因此可以更广泛地用于工艺控制。

This project will explore the use of optical methods such as resonantly-enhanced fluorescence for bacterial identification. We will build on the photonic sensor capability already developed together with P&G in a previous project and adapt the instrumentation accordingly. Pilot results have already indicated that our guided mode resonance (GMR) sensor modality can resonantly enhance fluorescence emission. We will build on these results and use them to study the bacteria forming the biofilm in more detail; we aim to differentiate between gram-positive and gram-negative bacteria as a first step. Identifying the bacterial species in more detail, and therefore the source of contamination in the process fluid, is more challenging, but feasible. In addition to providing much better information about bacterial contamination, this technique may also be capable of identifying the chemical mixture of the process liquid, so can be used for process control more generally.