Individualized Expert Systems for Weight Management

描述（由申请人提供）：超重和肥胖的患病率 在过去的二十年里急剧增加。超重和肥胖， 这是第二大可预防的死亡原因， 挑战在于它增加了慢性疾病的风险，包括冠心病 心脏病和全因死亡率。基于诊所的体重计划 管理费用昂贵，只为一小部分人服务。 需要以人口为基础的行为改变方案， 更经济有效地降低风险人群的百分比。初步研究 跨理论模型（TTM）在体重管理中的应用 表明该模型具有指导有效开发的潜力 多行为干预。该快速通道提案的第一阶段包括 定制和可行性测试阶段匹配，个性化， 基于TTM的交互式干预。可行性包括主动性 招募60%的合格参与者（n=250）参加一项 随机临床试验和评估干预的可接受性 材料.计算机化的专家系统干预和阶段匹配手册 积极主动地提供给全体人口， 目标健康行为以及体重。以TTM为基础 将提供专家们认为必要的理论框架 制定更有效和更具成本效益的干预措施。 拟定商业应用： 建议的TTM为基础的专家系统重量管理干预是能够 高招募率、准确评估和个性化干预， 在人口基础上创造高影响力的能力。 我们设想这样的互动 通过邮寄或电子邮件以相对较低的成本向全体人口提供技术， 通过Internet或Intranet。 商业应用包括营销到医疗保健 提供者，即管理式护理组织，以及分担 医疗费用。

DESCRIPTION (Provided by applicant): The prevalence of overweight and obesity has increased dramatically over the last two decades. Overweight and obesity, the second leading preventable cause of death, poses a major public health challenge in that it increases the risk of chronic diseases, including coronary heart disease, and all-cause mortality. Clinic-based programs for weight management are costly and serve only a small percentage of individuals. Population-based behavior change programs are needed to reach larger percentages of at risk individuals more cost-effectively. Preliminary research on the application of the Transtheoretical Model (TTM) to weight management suggests that the model has the potential to guide the development of effective multiple-behavior interventions. Phase I of this Fast-Track proposal involves the customization and feasibility testing of a stage-matched, individualized, interactive intervention based on the TTM. Feasibility includes proactively recruiting 60 percent of eligible participants (n=250) to participate in a randomized clinical trial and evaluating acceptability of the intervention materials. Computerized expert system interventions and stage-matched manuals delivered proactively to entire populations can have unprecedented impacts on the targeted health behaviors as well as weight. Using the TTM as the basis will provide the theoretical framework that experts have indicated is necessary to develop more effective and cost-effective interventions. PROPOSED COMMERCIAL APPLICATION: The proposed TTM based expert system weight management intervention is capable of high recruitment rates, accurate assessment, and individualized interventions that have the ability to create high impact on a population basis. We envision such interactive technologies for entire populations delivered at relatively low costs through the mail or over the Internet or an Intranet. Commercial applications include marketing to healthcare providers, namely managed care organizations, and employers who share the burden of healthcare expenses.