Gabapentin in the treatment of idiopathic chronic cough: a randomised double-blind placebo-controlled trial

需要更好的治疗方法来解决与慢性咳嗽相关的严重的生活质量损害。我们建议进行一项双盲、安慰剂对照研究，比较口服加巴喷丁治疗对特发性咳嗽患者咳嗽反射严重程度和咳嗽特异性生活质量的疗效(和安全性)。其优势在于强有力的设计，客观评估技术的使用，以及对咳嗽新治疗方式的研究。

Better treatment approaches are needed to address the significant quality of life impairment associated with chronic cough. We propose to conduct a double-blind, placebo controlled study comparing the efficacy (and safety) of oral gabapentin therapy on cough reflex severity and cough-specific quality of life in people with idiopathic cough. The advantages are a strong design, use of objective assessment techniques, and investigation of a new treatment modality for cough.