MSM/WCI Partnership To Investigate Mechanisms of Prostate Cancer: Planning Stage

优先级设定阶段 第一个试点项目(戴维森博士和谢家华博士)经过了充分的构思、计划和人员配备。因此，这 项目将在获得资金后立即实施。试点项目2将在第一年由一名 优先级设置过程如下所述。 我们选择了一个由6名癌症调查人员组成的内部咨询委员会：两名首席PI 另加来自每个机构的2名额外成员： 亚历克·J·戴维森博士是解剖学和神经生物学系的助理教授， 神经科学研究所和昼夜节律和睡眠障碍计划的成员。戴维森博士 四年来一直致力于生物钟和癌症之间的关系的研究， 目前，NCI授予的R21的PI用于在大鼠肝细胞癌模型中研究这一问题。他是 此拨款申请的MSM Lead-PI。 桑德拉·哈里斯-胡克，博士，负责赞助研究的副总裁兼副院长 MSM的行政管理和莫尔豪斯的少数民族生物医学研究支持计划主任 医学院，一个致力于培养未来生物医学研究学者的项目。使用 在细胞生物学方面的专业培训，以及心血管病理学的研究生重点，哈里斯博士- 胡克在血管细胞生物学领域工作了20多年，研究内皮功能障碍 参与动脉粥样硬化的发病机制。虽然她的主要研究领域是血管生物学，但她 还对如何加强基础、临床和基于人群的研究的整合感兴趣 以解决健康方面的差距。哈里斯-胡克博士自1983年以来一直在MSM教职员工。 丹尼尔·布鲁门撒尔，医学博士，公共卫生硕士，社区卫生和预防医学部主任 莫尔豪斯医学院预防研究中心(中国)首席研究员。这个 中华人民共和国的使命是促进非裔美国人疾病预防领域的科学知识 并传播新的信息和预防战略。具体来说， 布鲁门撒尔博士是中华人民共和国癌症预防和控制研究网络的PI，其使命是 是在少数族裔社区加快采用循证癌症预防和控制。

Priority-Setting Stage Pilot Project #1 (Drs. Davidson and Hsieh) is fully conceived, planned and staffed. Consequently this project will be implemented immediately upon funding. Pilot project #2 will be selected during Year 1 by a Priority-setting process described as follows. We have selected an Internal Advisory Committee comprised of 6 cancer investigators: The two Lead Pis plus 2 additional members from each institution: Alec J. Davidson, PhD is an assistant professor in the Department of Anatomy and Neurobiology, and a member of the Neuroscience Institute and Circadian Rhythms and Sleep Disorders Program. Dr. Davidson has been pursuing research on the relationship between circadian clocks and cancer for 4 years, and is currently PI of an R21 grant from NCI to investigate this issue in a rat model of hepatocellular carcinoma. He is the MSM Lead-Pi of this grant application. Sandra Harris-Hooker, PhD is the Vice President and Associate Dean for Sponsored Research Administration at MSM, and the Director of the Minority Biomedical Research Support Program at Morehouse School of Medicine, a program dedicated to the development of future biomedical research scholars. With professional training in Cell Biology, and postgraduate emphasis in Cardiovascular Pathology, Dr. Harris- Hooker has worked in the area of vascular cell biology for over 20 years, studying enddthelial dysfunctions involved in the pathogenesis of atherosclerosis. While her primary research area is vascular biology, she is also interested in ways by which to enhance the integration of basic, clinical and population-based research in order to address disparities in health. Dr. Harris-Hooker has been on the MSM faculty since 1983. Daniel Blumenthal, MD, MPH, is Chairman of the Department of Community Health and Preventive Medicine and Principal Investigator of the Morehouse School of Medicine Prevention Research Center (PRC). The mission of the PRC is to advance scientific knowledge in the field of prevention of disease in African American and other minority communities and to disseminate new information and strategies of prevention. Specifically, Dr. Blumenthal is PI of the Cancer Prevention and Control Research network within the PRC, whose mission it is to accelerate the adoption of evidence-based cancer prevention and control in minority communities.