A Novel Caries Prevention and Treatment System

描述（由申请人提供）：本研究计划的具体目标是开发一种低成本的激光龋齿预防和治疗系统，以有效减少或消除儿童和成人的龋齿。尽管过去几十年来龋齿发病率大幅下降，但仍有很大比例的儿童和成人的恒牙存在未经治疗的龋齿证据。此外，龋齿的下降在1990年代达到了一个平台。目前有许多方法可用于龋齿的预防和治疗。但是，它们受到其高成本、有限的可用性或有效性或缺乏长期抗龋性的限制。因此，需要新的方法来解决这些关键问题，并提供可以完全预防龋齿的低成本、长期解决方案。Creare的创新是龋齿预防和治疗系统（CRTS）。这种新型系统将标准氟化物治疗与低功率、低成本、连续波激光相结合，几乎完全抑制牙釉质脱矿。新的方法来测量实时搪瓷温度将是不可分割的系统。该硬件将与基于模型的自适应控制软件相结合，以精确控制搪瓷温度。通过这样做，我们的创新将最大限度地提高治疗效果，同时提高易用性并消除对敏感组织的损害风险。我们创新的低成本将使更多的人能够获得关键的龋齿管理和治疗，这对高危儿童和成人尤为重要。我们的新系统将提高龋齿预防的可负担性、可获得性、有效性、实用性和安全性。

DESCRIPTION (provided by applicant): The specific aim of this research program is the development of a low-cost, laser-based caries prevention and treatment system to effectively reduce or eliminate caries in children and adults. Even with the substantial decline in caries that has occurred over the last several decades, a substantial percentage of children and adults have evidence of untreated caries in their permanent teeth. Furthermore, the decline in caries reached a plateau during the 1990s. Many methods are currently available for caries prevention and treatment. However, they are limited by their high cost, limited availability or effectiveness, or lack of long- term caries resistance. Hence, new approaches are needed to address these key issues and provide a low- cost, long-term solution that can prevent caries altogether. Creare's innovation is the Caries Prevention and Treatment System (CRTS). This novel system combines a standard fluoride treatment with a low-power, low-cost, continuous-wave laser to almost completely inhibit enamel demineralization. Novel methodologies to measure the real-time enamel temperature will be integral to the system. This hardware will be combined with model-based adaptive control software to precisely control the enamel temperature. In so doing, our innovation will maximize the effectiveness of treatment while improving ease of use and eliminating the risk of damage to sensitive tissues. The low cost of our innovation will enable increased access to critical caries management and treatment, which is of particular importance to high-risk children and adults. Our novel system will improve the affordability, access, effectiveness, practicality, and safety of caries prevention.