PSYCHOSOCIAL CORE

心理社会核心对参与临床核心的所有受试者的主要照顾者以及MCI和AD患者的家庭成员进行全面评估，纵向跟踪他们，并根据要求为他们提供咨询。常规的结构化多方面评估分为两部分：第一部分包括抑郁、焦虑、社会网络和支持以及生活质量的测量;第二部分测量家庭冲突、行为问题和照顾者反应、照顾者评价、正式和非正式支持利用以及与照顾有关的其他具体特征。AD患者的家属完成整个评估。MCI受试者、其研究伴侣和认知正常但不是看护者的受试者仅完成本评估的第一部分。 在临床核心的每次诊断评估结束时，心理社会核心的顾问与受试者、主要照顾者（如果适当）和其他家庭成员举行会议。咨询工作人员可以响应帮助和信息的请求，是一个用户友好的资源，也是中心受试者和其他中心工作人员之间的联系。他们定期给心理社会核心小组的所有参与者打电话进行跟踪。他们的活动有助于招募新的受试者，留住现有的受试者， 受试者参与尸检跟踪和研究。心理社会核心数据是纽约大学心理社会研究计划的研究资源，也是该领域其他合作研究人员的资源。心理社会核心包括一个全面的遗传咨询和教育计划，这将服务于NIA遗传学倡议和ADCC附属研究人员在遗传学和蛋白质组学方面的目标，并提供数据，以扩展我们对心理社会干预的评估，包括制定有效的咨询和 为有关受试者和家庭成员提供有关AD遗传风险的支持。大型数据库和受试者库，我们将继续向其中添加新的受试者， 信息，将是一个宝贵的研究资源本身，并促进制定新的研究，以改善护理人员和病人的福祉。

The Psychosocial Core conducts a comprehensive assessment of the primary caregivers of all subjects participating in the Clinical Core, and family members of those with MCI and AD, follows them longitudinally and provides them with counseling on request. The routine structured multifaceted assessment is in two parts: the first part includes measures of depression, anxiety, social network and support and quality of life; the second part measures family conflict, behavior problems and caregiver reaction, caregiver appraisal, formal and informal support utilization and other specific characteristics related to caregiving. Family members of patients with AD complete the entire assessment. Subjects with MCI, their study partners and cognitively normal subjects who are not caregivers complete only the first part of this assessment. At the conclusion of every diagnostic evaluation of the Clinical Core, counselors of the Psychosocial Core conduct conferences with the subject, primary caregiver (if appropriate) and other family members. The counseling staff is available to respond to requests for help and information, are a user-friendly resource and a link between center subjects and other center staff. They make regular follow-up telephone calls to all participants in the Psychosocial Core. Their activities facilitate recruitment of new subjects, retention of current subjects and participation of subjects in autopsy tracking and in research studies. The Psychosocial Core data is a resource for the research of the NYU Psychosocial Research Program, and for other collaborating investigators in the field. The Psychosocial Core includes a comprehensive genetic counseling and education program, which will serve the goals of the NIA-Genetics Initiative and ADCC-affiliated researchers in genetics and proteomics and provide data to extend our evaluations of psychosocial interventions to include development of effective counseling and support for concerned subjects and family members about genetic risk for AD. The large database and subject pool, to which we will continue to add new subjects and longitudinal information, will be a valuable research resource in its own right and foster the formulation of new research to improve caregiver and patient well-being.