Towards a better understanding of cardio and cerebrovascular diseases

研究潜在影响：确定影响终身健康、老龄化和慢性疾病发展的生物和社会因素，并利用研究结果设计和测试促进健康老龄化的干预措施。发现医学成像（如超声心动图、磁共振）的新特征，以预测主要临床结果（如心脏病发作、住院、死亡）。2 .使用新型远程监测技术（如可穿戴设备和移动健康设备），确定对长期心血管健康有重大影响的趋势。3 .基于脑MRI影像和临床资料，建立新的脑血管疾病演变预测模型。提高对脑血管病变与认知之间可能联系的认识。研究方法：项目将涉及将数据科学和机器学习技术应用于生理和成像数据，以更好地了解正常衰老和疾病过程，其总体目标是改善心脑血管疾病和认知能力下降的预防，促进健康老龄化。该奖学金由MRC终身健康和老龄化部门与医学图像计算中心合作提供。由MRC LHA、i4health CDT和BHF加速器奖共同资助

Research Potential Impact:To identify biological and social factors that affect lifelong health, ageing and the development of chronic disease, and to use findings to design and test interventions that enhance healthy ageingResearch Aims:1. Discover novel features in medical imaging (e.g. echocardiography, magnetic resonance) to predict major clinical outcomes (e.g. heart attack, hospital admission, death).2. Use novel remote monitoring techniques (e.g. wearable devices and mobile Health devices) to identify trends significantly impacting on long-term cardiovascular health.3. Develop new predictive models of cerebrovascular disease evolution based on brain MRI imaging and clinical data.4. Improve the understanding of the possible links between cerebrovascular lesions and cognition.Research Methodology:Project will involve applying data science and machine learning techniques to physiological and imaging data to gain better insight into normal ageing and the disease process, with the overarching aim of improving prevention of cardio- and Cerebro-vascular disease and cognitive decline and promoting healthy ageing.Studentship is available in a partnership between the MRC Unit for Lifelong Health and Ageing, and the Centre for Medical Image Computing. Funding jointly from the MRC LHA, i4health CDT and the BHF accelerator award