AI-enhanced ultra-thin optical shape mapping probes for manufacturing and medicine

精确测量物体的内部几何形状对制造、检验和医学至关重要。应检查内部结构的制成品包括发动机部件、组织支架、生物医学植入物和假肢以及药物输送装置。在制造中，中空部件通常使用x射线计算机断层扫描（CT）进行检查，但这可能非常昂贵，特别是在需要高分辨率的情况下，并且小型敏捷制造商无法使用。此外，它通常不能很准确地检测内部表面纹理，可能仅限于某些材料（例如，它不能与铅一起工作），并且可能使工厂工人暴露在危险的x射线辐射中。在生物医学领域也出现了类似的问题，特别是在结肠镜检查过程中，外科医生正在寻找可疑的癌前生长，称为息肉。息肉有许多不同的形状和大小，从扁平到大而圆。不同的形状可以代表或多或少侵袭性的癌症，用传统的成像方法很难发现。因此，获得这些物体的三维信息可以提供重要的信息，但需要一种超薄且足够灵活的形状测量工具，以适应内窥镜[3]。a . Thompson， I. Maskery和R. K. Leach，“用于增材制造的x射线计算机断层扫描：综述”，《测量科学与技术》，第27卷，第27期。7, p. 072001, 2016N. G. Burgess， L. F. Hourigan， S. a . Zanati， G. J. Brown， R. Singh， S. J. Williams， S. C. Raftopoulos， D. Ormonde, a . Moss， K. Byth，等，“结肠内镜下粘膜切除术患者隐性侵袭性癌症的风险分层：一项大型多中心队列研究”，《胃肠病学杂志》，第153卷，第1期。3, pp. 732-742, 2017M. Visentini-Scarzanella， H. Kawasaki， R. Furukawa， M. A. Bonino， S. Arolfo， G. L. Secco， A. Arezzo， A. Menciassi， P. Dario和G. Ciuti，“用于胃肠道息肉大小测量的结构光激光探针：初步比较研究”，内窥镜国际开放，第6卷，第6期。5, pp. E602-E609, 2011

Accurately measuring internal geometries of objects is critical for manufacturing, inspection and medicine. Examples of manufactured products whose internal structure should be inspected includes engine parts, tissue scaffolds, biomedical implants and prosthetics, and drug delivery devices. In manufacturing, hollow parts are typically inspected using X-ray computed tomography (CT) but this can very expensive, particularly if high resolution is required, and is not accessible to smaller, agile manufacturers. Further, it often cannot detect internal surface textures accurate well [1], may be limited to application to certain materials (e.g. it cannot work with lead) and may expose factory workers to dangerous X-ray radiation. A similar problem arises in biomedicine, particularly during colonoscopy procedures where surgeons are look for suspicious pre-cancerous growths, termed polyps. Polyps take many different shapes and sizes from flat to large and round. Different shapes can represent more or less aggressive cancers and be challenging to spot using conventional imaging [2]. Therefore, obtaining 3D information of these could provide important information but requires a shape measurement tool that is ultrathin and flexible enough to fit inside an endoscope [3].References[1] A. Thompson, I. Maskery, and R. K. Leach, "X-ray computed tomography for additive manufacturing: a review," Measurement Science and Technology, vol. 27, no. 7, p. 072001, 2016.[2] N. G. Burgess, L. F. Hourigan, S. A. Zanati, G. J. Brown, R. Singh, S. J. Williams, S. C. Raftopoulos, D. Ormonde, A. Moss, K. Byth, et al., "Risk stratification for covert invasive cancer among patients referred for colonic endoscopic mucosal resection: a large multicenter cohort," Gastroenterology, vol. 153, no. 3, pp. 732-742, 2017.[3] M. Visentini-Scarzanella, H. Kawasaki, R. Furukawa, M. A. Bonino, S. Arolfo, G. L. Secco, A. Arezzo, A. Menciassi, P. Dario, and G. Ciuti, "A structured light laser probe for gastrointestinal polyp size measurement: a preliminary comparative study," Endoscopy International Open, vol. 6, no. 05, pp. E602-E609, 201