Core--Botanical

植物学核心将通过执行以下任务促进所有三个研究项目、动物核心和先导研究计划的工作：以温室为基础的源植物栽培和生物活性物质生产的优化，为中心的研究生产植物疗法，临床前和临床前研究和先导研究计划，活动指导下的生物活性物质分离和它们相互作用的表征，为研究活动和临床前和临床前研究提供分析和结构化学支持，质量控制和植物学认证。植物学核心还将开展致力于发现新的植物疗法的研究活动，这将由先导研究计划进行研究。植物核心将从罗格斯大学(Raskin-Core Leader博士)选址并领导，一些工作将分包给路易斯安那州立大学农业中心(Liu-Core共同领导博士)。CORE将利用最近开发的方法来发现、表征、标准化和生产生物活性物质，这些生物活性物质在开发目前正在进行临床试验的新型植物药物方面被证明是成功的。它将有效地利用拉斯金博士实验室可用的资源、专业知识、设备和温室设施作为 行业支持的项目和第n-NSF-USDA资助的天然产品生物勘探国际合作生物多样性组织(ICBG)赠款的结果。

The Botanical Core will facilitate the work of all three Research Projects, the Animal Core and the Pilot Research Programs by performing the following tasks: Greenhouse-based cultivation of source plants and optimization of bioactives production, Production of botanical therapeutics for the Center's research, pre-clinical and clinical studies and pilot research programs, Activity guided isolation of bioactives and characterization of their interactions, Analytical and structural chemistry support for the research activities and pre-clinical and clinical studies, Quality control and botanical authentication. The Botanical Core will also perform research activities dedicated to discovering novel botanical therapeutics, which will be studied by the Pilot Research Programs. The Botanical Core will be located and led from Rutgers University (Dr. Raskin - Core Leader) with some work subcontracted to Louisiana State University Agricultural Center (Dr. Liu - Core Co-Leader). The Core will utilize recently developed methods for the discovery, characterization, standardization and production of bioactives proven successful in developing novel botanicals that are currently in clinical trials. It will effectively leverage resources, expertise, equipment and greenhouse facilities available at Dr. Raskin's laboratory as a result of industry-supported programs and NTH-NSF-USDA-funded International Cooperative Biodiversity Groups (ICBG) grant for natural product bioprospecting.