Arthritis Research Conference 2007

描述(申请人提供)：本提案要求为2007年关节炎研究会议提供部分资金，这是我们的第六个两年一度的会议，将由关节炎基金会、美国风湿病学会和国家关节炎、肌肉骨骼和皮肤病研究所联合主办。会议将于2007年4月20日至22日在佐治亚州亚特兰大的长荣万豪会议中心举行。其主要目的是通过一个有利于讨论新的技术方法和启动新的科学合作的多学科会议环境，增加青年研究人员的教育和网络机会。北美的所有关节炎研究实习生都将被邀请参加。我们还将邀请根据他们的专长和兴趣确定的选定的高级研究人员，他们很可能对会议的刺激和富有成效的环境作出贡献并从中受益。参会人数将限制为400人。全体讲座将由杰出的研究人员提供，他们还将主持会议和讲习班，并在会议期间与受训者互动。这次全体会议的题目是.关节炎医学的翻译：从工作台到床边。会议将致力于提供NIH扩大翻译努力的计划的概述，并讨论基本的分子和细胞观察已成功发展为风湿病的新的、安全和有效的治疗方法的几个例子。基础科学研讨会将专门讨论关节中的信号和调节，以及细胞内通路如何有助于关节发育，以及在其他情况下与疾病相关的这些组织的破坏。临床科学研讨会将集中讨论这一主题：炎症性疾病的新视角。将举行一场特别的临床成果研究研讨会，并为选定的学员举办八个研讨会，介绍他们的研究，其中包括：类风湿性关节炎和相关小鼠模型的发病机制；临床措施和狼疮的发病机制；关节软骨生物学和组织工程修复策略；风湿病的临床结果和流行病学；组织工程学和基因疗法；风湿病研究的新兴技术；细胞外基质和炎症的调节；以及系统性红斑狼疮和自身免疫的发病机制。此外，还将有三个海报展示环节，所有剩下的学员都将有机会展示他们的作品。总体而言，会议的中心目标是在非正式气氛中提供一次互动会议，促进全面讨论关节炎发病机制和相关肌肉骨骼疾病的科学基础。会议将努力促进实习生和来自不同背景的资深科学家之间有意义的互动，以讨论当前的工作，并鼓励新的倡议和协作互动。

DESCRIPTION (provided by applicant): This proposal requests partial funding for Arthritis Research Conference, 2007, our sixth biennial conference, which will be held under the joint sponsorship of the Arthritis Foundation, the American College of Rheumatology, and the National Institute of Arthritis, Musculoskeletal and Skin Diseases. The meeting will be held on April 20-22, 2007 at the Evergreen Marriott Conference Center, Atlanta GA. The primary aim is to enhance the educational and network opportunities of young investigators, through a multi-disciplinary conference environment that is conducive to discussions of new technical approaches and the initiation of novel scientific collaborations. All arthritis research trainees in North America will be invited to attend. We will also invite selected senior researchers, identified based on their expertise and interests, who will most likely contribute to, and benefit from the stimulating and productive environment of the Conference. Participation will be limited to 400 attendees. Plenary lectures will be provided by accomplished distinguished investigators, who will also chair sessions and workshops, and interact with trainees during the Conference. The plenary session, entitled .Translation in Arthritis Medicine: Bench to the Bedside., will be devoted to providing an overview of NIH plans for extending translational efforts, and talks on several examples in which basic molecular and cellular observations have been successfully developed into novel and safe and effective therapies in the rheumatic diseases. The Basic Science Symposium will be devoted to the topic of .Signaling and regulation in the Joint, and how intracellular pathways contribute to joint development, and in other settings disease-associated destruction of these tissues. The Clinical Sciences Symposium will focus on the topic .New Perspectives on Inflammatory Disease. There will be a special .Clinical Outcomes Research Symposium., as well as eight workshops will be held for selected trainees to present their research, which will include: Pathogenesis of RA and related murine models; Clinical measures and pathogenesis of Lupus; Biology of articular cartilage and tissue engineering repair strategies; Clinical outcomes and epidemiology of rheumatic diseases; Tissue engineering and gene therapy; Emerging technologies for the study of rheumatic diseases; Regulation of extracellular matrix and Inflammation; and SLE and pathogenesis of autoimmunity. In addition, there will be three poster sessions, at which all remaining trainees will have an opportunity to present their work. Overall, the central goal of the conference is to provide an interactive meeting in an informal atmosphere that facilitates comprehensive discussion of the scientific basis of arthritis pathogenesis and related musculoskeletal diseases. The Conference will strive to promote meaningful interactions between trainees and senior scientists from very diverse backgrounds to discuss current work, as well as stimulate new initiatives and collaborative interactions.