Structural, Functional & Evolutionary Genomics Gordon Conference

描述（由申请人提供）：本提案请求资金支持2007年7月29日至8月3日在英国Hinxton的Wellcome Trust Sanger研究所基因组中心举行的Gordon结构、功能和进化基因组学研究会议，以及2009年的后续会议。结构、功能和进化基因组学GRC致力于在尽可能广泛的范围内对生物系统进行雄心勃勃的分析：全基因组和蛋白质组；在生物网络的背景下基因和蛋白质功能的全面检查；并充分利用比较基因组学和进化理论的力量。该GRC的独特之处在于，它汇集了该研究的实验和计算/理论方面的专家。实验讲座向计算科学家介绍新的、有前途的数据集和实证结果。计算讲座为实验家提供了揭示其发现意义的新方法和算法，也提供了整合不同类型数据所需的理论框架。

DESCRIPTION (provided by applicant): This proposal requests funds to support the Gordon Research Conference on Structural, Functional & Evolutionary Genomics, July 29 - August 3, 2007, at the Wellcome Trust Sanger Institute Genome Center in Hinxton, UK, and for the subsequent meeting in 2009. The GRC on Structural, Functional & Evolutionary Genomics is devoted to ambitious analysis of biological systems at the broadest scale possible: full genomes and proteomes; full examination of gene and protein function in the context of biological networks; and full use of the power of comparative genomics and evolutionary theory. This GRC is unique in bringing together experts in both the experimental and computational / theoretical aspects of this research. Experimental talks introduce computational scientists to new, promising data sets and empirical results. Computational talks provide experimentalists with new methods and algorithms for revealing the significance of their findings and also offer the theoretical framework that is needed to integrate different types of data. The broad themes for the 2007 meeting are the evolution of gene regulation, non-protein-coding DNA, and regulatory networks; evolution of networks in the presence of noise; comparative genomics of gene expression; biodiversity and metagenomics; functional genomics; evolution of synthetic life; and contribution of comparative genomics to our understanding of the major transitions in life's evolution. The topics discussed in the meeting have broad relevance to understanding basic human biology. Specific topics including the function of non-coding DNA and the genomic architecture of complex traits are directly relevant to human disease, especially as technologies first developed for model organisms are applied to human. In addition to the scientific objectives, this GRC, in line with the broad goals of Gordon Conferences, strives to encourage mixing and interactions among a diverse scientific body. We aim to have representation from senior scientists and those just starting their scientific careers and to include, as much as possible, women and minorities. The GRC has an additional goal of encouraging scientific interchange between the US and Canada, Europe, Asia, and other scientific centers. In that regard, this GRC stands a chance to be particularly fruitful because it will be the first meeting at a new GRC site, Hinxton (UK), a major center of Genomics, Systems Biology, and Bioinformatics for the UK and Europe.