Training in Fundamental & Translational Neuroscience

描述（由申请人提供）： 基础和转化神经科学博士后培训。 本申请的目的是为杜克大学的博士后奖学金培训项目获得资金，该项目将有助于完成NINDS的使命-“减轻神经系统疾病的负担。“这项使命的关键是对年轻神经科学家进行出色的博士后培训。本申请描述了一个旨在促进完成这一使命的计划，该计划旨在培养基础和翻译神经科学家。这种做法的基本原理很简单。在我们看来，许多基础神经科学家未能充分认识到他们的工作对人类疾病的影响，因此错过了可能揭示疾病机制或更有效治疗的科学方向的机会。相反，许多翻译神经科学家未能完全掌握基础神经科学的一些原则和技术，从而限制了他们的科学方法的卓越性。本文所述的计划旨在促进基础和翻译神经科学家的博士后培训，使这两种类型的学员受益，从而为每个学员作为独立研究者的富有成效的职业生涯做好准备。在我们看来，杜克大学神经科学的这个新时代为实施这一新颖的培训计划提供了一个绝佳的机会。

DESCRIPTION (provided by applicant): Postdoctoral Training in Fundamental and Translational Neuroscience. The goal of this application is to obtain funding for a postdoctoral fellowship training program at Duke University that will facilitate accomplishing the mission of NINDS - "to reduce the burden of neurological disease." Critical to this mission is outstanding postdoctoral training of young neuroscientists. This application describes a program designed to facilitate accomplishing this mission, a program that seeks to train both fundamental and translational neuroscientists. The rationale for this approach is straightforward. In our view, many fundamental neuroscientists fail to fully appreciate the implications of their work for human disease and as a result miss opportunities for scientific directions that may shed light on mechanisms of disease or more effective therapy. Conversely, many translational neuroscientists fail to fully grasp some of the principles and techniques of fundamental neuroscience, thereby limiting the excellence of their scientific approaches. The program described herein seeks to promote the postdoctoral training of both fundamental and translational neuroscientists in ways that will benefit both types of trainees and thereby prepare each trainee for a productive career as an independent investigator. In our view, this new era in neuroscience at Duke University provides an outstanding opportunity to implement this novel training program.