The mechanisms of portable negative pressure wound therapy on wounds

负压治疗长期以来一直被认为是伤口治疗中的有价值的工具，以控制渗出液，提供屏障功能，在愈合过程中支持伤口，并帮助患者护理。新型负压器械（如皮科）提供便携式负压治疗，使患者和临床团队在使用中具有更大的灵活性。通过其专有技术，它具有独特的作用模式，能够将治疗传递到伤口以外的更广泛区域，包括伤口。该器械工作的生物学机制仍不清楚，可能有助于破译哪些患者对该器械反应最好，对适应症进行分层，并重要地确定可以进一步改进以改善伤口愈合的新机制。

Negative pressure therapy has long been established as valuable tool in wound therapy to control exudate, provide barrier function, support wounds through the healing process and help with nursing care of patients. New negative pressure devices such as the PICO provides portable negative pressure therapy enabling the patient and clinical teams far greater flexibility in use. It has a unique mode of action through its proprietary technology enabling delivery of therapy beyond the wound to wider regions including the peri wound. The biological mechanisms by which the device works remains unclear and may help decipher which patients best respond to the device, stratify indications, and importantly identify novel mechanisms that could be further advanced to improve on wound healing.