Medical Image Presentation: Structural Image Analysis

描述(由申请人提供) 在我们目前计划的三个项目都取得了巨大成功之后，我们已经 决定通过建立我们的新项目来增加我们计划项目的重点 其中一项计划，并正在为另外两项寻求单独的资金。 特别是，我们把这个节目的重点放在了对 基于我们的原理和方法的医学图像三维物体的几何结构 以培训为基础，在多个层面上开展工作的创新方法 图像集。该计划由四个项目和三个核心组成。其中之一 这些项目的重点是图像分析方法的开发和推广 基于多个比例级别的单个和多个对象模型， 中间级别的比例专门为代表人物而设计 物体的各方面。因为我们图像分析的成功 方法，现在是三个项目探索这种药物的医疗用途的时候了。 方法：研究方法。这三种方法中有两种侧重于对 脑与疾病辨别的几何结构关系 精神疾病的诊断。另一个医疗项目继续我们的 本节目的重点是放射治疗计划。为了支持 几何图像分析方法和医学图像分析方法的评价 术语，我们继续生物统计学的核心，我们在 开发用于验证图像分析方法的方法学。 最后，设施和管理核心为 其他项目。

DESCRIPTION (provided by applicant) Following strong successes in all 3 projects of our present program, we have decided to increase the focus of our program project by building our new program on one of them and are seeking separate funding for the other two. In particular, we focus this program on segmentation and discrimination of the geometric structure of 3D objects in medical images by our principled and innovative methods working at multiple levels of scale and based on training image sets. The program consists of four projects and three cores. One of the projects focuses on development and extension of image analysis methods based on single and multiple object models at multiple levels of scale, with the middle levels of scale specifically designed to represent the figural aspects of objects. Because of the successes of our image analysis methodology, it is now time for three projects to pursue medical uses of such methods. Two of these three focus on the segmentation of structures in the brain and discrimination of disease from their geometric structure in relation to the diagnosis of mental illnesses. The other medical project continues our present program's focus on radiotherapy treatment planning. To support the evaluation of the image analysis methods both geometrically and in medical terms, we continue the core on biostatistics, and we add a core on the development of methodology for validation of image analysis methods. Finally, a facilities and administration core provides infrastructure for the other projects.