Training Grant in Transfusion Medicine

描述(由申请人提供)： 这是一份修订后的NRSA申请(T32 HL69769)，请求为埃默里大学的输血医学计划(TMP)研究奖学金提供工资支持。如果得到资助，这笔赠款将为博士后研究员提供工资支持，让他们参加为期两年的密集实验室输血医学研究。该计划每年招收一名研究员，为期5年，旨在满足公认的对输血医学基础、翻译和跨学科研究培训的需求。需要这种培训来培养未来的输血和移植研究专家，以促进该专业的进一步增长和研究发展，并使其有能力为其他领域的研究和临床实践作出贡献。以前确定的计划优势包括：首席调查员/计划主任；将培训计划作为一个小规模计划组织起来，重点放在高质量的候选人和研究项目上；拥有强大的科学、资金和培训记录的高级教员的参与；以及为教育研究员和对培训计划进行外部评估提供具体机制。我们对先前提交的文件中确定的两个薄弱环节进行了改进：1)修订表II， 2)通过加强外部咨询委员会提供的监督，解决输血医学方案的“年轻人”问题。为了进一步强调该项目致力于提供直接的个人努力来培训博士后研究员，教师导师仅限于那些在培训职业生涯早期研究人员方面拥有大量资金和经过证明的记录的人。为了强调输血医学研究的转化性和跨学科性质，计划单元被略微修改为：1)输血和移植传播的病原体；2)基础输血和移植免疫学；以及3)干细胞和体细胞移植。我们感谢评审者提出的许多积极和建设性的意见，并注意到埃默里没有其他部门、部门或项目提供输血医学的研究培训，也没有其他资金用于此类培训。

DESCRIPTION (provided by applicant): This is a revised NRSA application (T32 HL69769) requesting salary support for a Transfusion Medicine Program (TMP) Research Fellowship at Emory University. If funded, this grant would provide salary support for post-doctoral fellows to participate in a two-year, intensive laboratory experience in transfusion medicine research. The program, which would enroll one fellow per year for a 5-year period, aims to fill the acknowledged need for basic, translational, and interdisciplinary research training in transfusion medicine. Such training is needed to develop future specialists in transfusion and transplantation research in order to contribute to the further growth and research development of the specialty and its ability to contribute to other fields of research and clinical practice. Program strengths previously identified include: the Principal Investigator/Program Director; the organization of the training plan as a small-scale program emphasizing high-quality candidates and research projects; the involvement of senior faculty with strong scientific, funding, and training records; and the provision of specific mechanisms for educating fellows and externally evaluating the training program. We have improved upon the 2 areas of weakness identified in the earlier submission by: 1) revising Table II, Appendix I to more clearly represent faculty training histories; and 2) addressing the "youth" of the transfusion medicine program by reinforcing the oversight to be provided by the External Advisory Board. To further underscore the program's commitment to providing direct personal effort in training post-doctoral research fellows, the faculty mentors have been limited to only those with significant funding and proven track records in training early-career investigators. To emphasize the translational and interdisciplinary nature of transfusion medicine research, the program units have been slightly revised as follows: 1) Transfusion- and transplantation-transmitted pathogens; 2) Basic transfusion and transplantation immunology; and 3) Stem and somatic cell transplantation. We are appreciative to the reviewers for the many positive and constructive comments, and note that no other department, division, or program at Emory provides research training in transfusion medicine, and no other funds for such training are available.