Genomic and functional analyses of a novel gene implicated in type 1 diabetes

我们最近发现了一种促进青少年糖尿病发展的新基因。不幸的是，人们对这种基因的功能知之甚少。为了更好地理解这种基因是如何影响免疫系统并导致疾病的，我们培育了一种独特的小鼠品系，这种品系具有这种基因的功能失调拷贝。这些小鼠将使我们能够表征这种基因，并有可能在糖尿病预防方面建立一个新的研究领域。

We have recently discovered a novel gene that contributes to the development of juvenile diabetes. Unfortunately, very little is known about the function of this gene. To better understand how this gene affects the immune system and contributes to disease, we have generated a unique mouse strain that has a dysfunctional copy of this gene. These mice will enable us to characterise this gene and potentially establish a new area of research in diabetes prevention.