Multidisciplinary Training in Molecular Endocrinology

描述（由申请人提供）： 本延续提案要求支持范德比尔特大学医学中心（VUMC）的分子内分泌学培训计划（METP）。在生物化学，癌症生物学，细胞和发育生物学，微生物学和免疫学，分子生理学和生物物理学，病理学和药理学系的39名教师构成了METP的导师。在这组中，有34名教师拥有稳定，资金充足的课程和培训经验，5名是新的研究人员;鉴于我们的机构招聘计划，未来几年将在初级和高级级别进行更多的任命。导师组是一个异常多样化和有才华的群体，他们的工作涵盖了分子内分泌学的范围。这些导师在以下一般领域进行研究：1）信号转导2）基因表达的激素调节3）代谢调节和4）β细胞发育和功能。10名博士前和4名博士后学员的稳定水平的要求是合理的，其依据是导师指导的研究项目的数量，规模和质量以及机构对扩大学员招聘的承诺。 所有METP学员都是在导师提名后，根据咨询委员会的建议任命的。博士后培训生拥有博士学位。或者医学博士度或两者。严格的深入研究培训是博士前和博士后培训计划的重点。然而，METP还确保所有学员通过分子内分泌学和代谢调节课程接受广泛的教学教育。此外，所有METP学员参加范德比尔特糖尿病中心（VDC）系列研讨会，并会见来访的科学家。该方案还提供关于正确使用放射性同位素、处理有毒和危险材料的适当程序以及在研究中负责任行为的正式培训，METP学员还可以参加正式的职业咨询方案，以处理与就业机会有关的问题。 在METP的博士前培训如下，在生物医学科学（IGP）的跨学科研究生课程收到。IGP招收范德比尔特生物医学科学的所有博士前学员，并提供第一年的核心课程。它还监督参与的八个部门之间的实验室轮换和导师选择。这种集中招聘大大增加了进入范德比尔特并随后竞争METP支持的学生的数量和质量。质量评估的基础上GPA和GRE成绩，推荐信和以前的研究经验。IGP和METP在促进少数民族学生入学方面都非常成功。

DESCRIPTION (provided by applicant): This continuation proposal requests support for the Molecular Endocrinology Training Program (METP) at Vanderbilt University Medical Center (VUMC). Thirty nine faculty members in the departments of Biochemistry, Cancer Biology, Cell and Developmental Biology, Microbiology and Immunology, Molecular Physiology and Biophysics, Pathology and Pharmacology constitute the preceptors of the METP. Of this group thirty four are established faculty with stable, well-funded programs and training experience and five are new investigators; given our Institutional recruiting plans, several more appointments at both junior and senior levels will be made in the next few years. The preceptor group constitutes an unusually diverse and talented group of individuals whose work covers the spectrum of molecular endocrinology. These preceptors conduct research in the general areas of: 1) signal transduction 2) the hormonal regulation of gene expression 3) metabolic regulation and 4) beta cell development and function. The request for a steady state level of 10 predoctoral and 4 postdoctoral trainees is justified on the basis of the number, size and quality of the research programs directed by the preceptors and the Institutional commitment to expanding the recruitment of trainees. All METP trainees are appointed upon the advice of an Advisory Committee after being nominated by a preceptor. Postdoctoral trainees have a Ph.D. or M.D. degree or both. Rigorous in-depth research training is the focus of both the pre- and postdoctoral training programs. However, the METP also ensures that all trainees receive a broad didactic education through courses in Molecular Endocrinology and Metabolic Regulation. In addition, all METP trainees attend the Vanderbilt Diabetes Center (VDC) seminar series and meet with the visiting scientists. The Program also provides formal training in the proper use of radioisotopes, in appropriate procedures of dealing with toxic and dangerous materials, and in the responsible conduct in research METP trainees also have access to a formal career counseling program to deal with matters that concern employment opportunities. Predoctoral training in the METP follows that received in the Interdisciplinary Graduate Program in Biomedical Sciences (IGP). The IGP recruits all predoctoral trainees in the biomedical sciences at Vanderbilt and provides a first year core curriculum. It also supervises laboratory rotations and preceptor selection among the participating eight Departments. This centralized recruitment has considerably increased the number and quality of students that enter Vanderbilt and subsequently compete for METP support. Quality is assessed on the basis of GPA and GRE scores, letters of recommendation and prior research experience. Both the IGP and METP have been very successful in promoting minority student admissions.