GYNECOLOGIC ONCOLOGY GROUP

该应用程序适用于妇科肿瘤组(GOG)CCOP研究基地。《妇科》 肿瘤组是治疗妇科癌症的主要临床试验小组，并开发了一种 积极开展癌症预防和控制计划。妇科肿瘤学小组的组成 包括妇科肿瘤学家、内科肿瘤学家、放射肿瘤学家、病理学家、护士肿瘤学家、 生物统计学家、实验室科学家、行为科学家、流行病学家等学科。The GOG 由妇科领导的社区调查小组的附属网络加强了 肿瘤学家。该网络由小型大学和/或大型社区医院组成，应作为 通过增加现有的和新的贡献，对预防计划的重要补充 CCOP组织为招募和登记患者提供更多机会 癌症预防试验。CCOP机构沿着典型的多部位内科肿瘤学的路线形成 合作小组将找到机会让患者参加由 GOG。然而，许多未来的预防研究将需要访问以前的患者组 在CCOP机构中未见。随着他们适应这些新的挑战，分支机构网络已经到位 将为预防计划的成功提供支持和领导。在以前的 作为一个研究基地，GOG的CCOP机构已经达到了治疗目标。谷歌失去了它的 由于CCOP未能达到预防目标而导致的研究基地状况。CCOP和CCOP的结合 预防成员妇科肿瘤附属机构应该纠正之前的不足。有耐心的 应计费用：在以前的研究基础资助下，患者对治疗试验的应计费用在#年令人满意 资助的每一年--1997至1999年。在预防方面，CCOP机构没有达到 提供了标准。虽然这一经验表明，GOG在癌症方面的要求 预防研究可能不同于其他研究基地开发的研究，它还表明 有一些CCOP组织可以应对这一挑战。调整的时间要求是 时间比预期的要长。然而，目前的RFA中有一项条款允许指定 合作临床试验组织的成员为预防成员。

This application is for the Gynecologic Oncology Group (GOG) CCOP Research Base. The Gynecologic Oncology Group is the premier clinical trial group in treatment of gynecologic cancers and has developed an active cancer prevention and control program. The composition of the Gynecologic Oncology Group includes gynecologic oncologists, medical oncologists, radiation oncologists, pathologists, nurse oncologists, biostatisticians, laboratory scientists, behavioral scientists, epidemiologists and other disciplines. The GOG is strengthened by an affiliate network of community-based investigative teams led by gynecologic oncologists. This network consists of small university and/or large community hospitals and should serve as a significant supplement in the prevention program by augmenting contributions from existing and new CCOP organizations in providing enhanced opportunities for recruitment and enrollment of patients into cancer prevention trials. The CCOP institutions formed along the lines of typical multi-site medical oncology cooperative groups will find opportunities to enter patients into treatment and prevention trials developed by the GOG. However, many of the future prevention studies will require access to patient groups previously not seen in CCOP institutions. As they adjust to these new challenges, the affiliate network already in place in the GOG will provide support and leadership in making the prevention program successful. In previous experiences as a Research Base, the GOG's CCOP institutions have met treatment goals. The GOG lost its Research Base status due to failure of the CCOPs to meet prevention goals. The combination of CCOP and Prevention Member Gynecologic Oncology Affiliate institutions should correct that previous deficit. Patient Accrual: Under the previous Research Base funding, patient accrual to treatment trials was satisfactory for each year of the grant - 1997 through 1999. In terms of prevention, the CCOP institutions did not meet the standards provided. While that experience showed that the requirements of the GOG in terms of cancer prevention studies may be different from those developed by other Research Bases, it also showed that there were CCOP organizations that could meet the challenge. The time requirement for adjustment was longer than anticipated. However, there is a provision in the current RFA allowing the designation of members of the cooperative clinical trial organization as Prevention Members.