NIDA Clinical Trials Network - New York Node

描述（由申请人提供）： CTN的纽约节点是一个学术中心、临床项目以及地方和区域机构的联盟，在成瘾性疾病的研究、培训、服务提供、政策制定、资助和宣传方面有着富有成效的合作记录。该联盟提供了丰富的人才，并有机会在纽约市，纽约州和区域广泛的临床和政策资源。这些研究者、提供者和政策制定者共同拥有广泛的大规模临床试验专业知识、广泛的研究兴趣、独特的治疗能力以及广泛的服务和政策经验。在过去的五年中，纽约节点建立了有效的内部和外部工作关系，为国家CTN基础设施做出了贡献，建立了坚实而灵活的本地基础设施，并作为牵头节点和参与节点有效地实施了协议。纽约节点在2002年3月组织NIDA纽约混合会议方面发挥了关键作用，并成功地与新兴的地方联盟合作，促进CTN创新的传播和采用。NY Node的供应商和研究人员参与规划和开发三项研究（START，ADHD和处方阿片类镇痛药依赖协议），这些研究将在未来几年内成为NIDA的高度优先事项，我们的CTP都处于测试和引入医疗干预措施的有利地位。本提案是根据CTN五年的经验以及我们对CTN的成就和面临的挑战的评估提出的。我们的整体主题方法利用了CTN和Node迄今为止的成就，并解决了未来的挑战。我们带来了新的调查人员和专业知识，我们描述了一个增强的科学实践模型CTN研究，我们扩大与州和地方政府机构的关系，使这一点，我们提出了一个研究概念，在这个框架内工作。主题包括接触初级保健提供者，扩大相关成果，与可以分担研究费用和促进收养的机构建立伙伴关系，以及解决报销和护理组织系统问题。我们的研究理念建立在这些主题的基础上，以扩大CTN的覆盖范围，并提高CTN研究产生影响的可能性，并在更广泛的层面上改善医疗保健。

DESCRIPTION (provided by applicant): The New York Node of the CTN is a consortium of academic centers, clinical programs and local and regional agencies with a long track record of fruitful collaboration in research, training, service delivery, policy-making, funding and advocacy for the addictive disorders. The consortium offers a rich array of human talent and has access to vast clinical and policy resources in NY City, NY State and regionally. Together, these investigators, providers and policy-makers have extensive large-scale clinical trials expertise, a broad range of research interests, unique treatment capacity and extensive services and policy experience. Over the past five years the NY Node has built effective internal and external working relationships, it has contributed to the national CTN infrastructure, it has built a solid and flexible local infrastructure and it has effectively implemented protocols as a Lead Node and as a Participating Node. The NY Node played a key role in organizing NIDA's NY Blending Conference in March, 2002, and has successfully worked with emerging local coalitions to foster dissemination and adoption of CTN innovations. NY Node providers and researchers are involved in planning and developing three studies (START, ADHD and prescription opiate analgesic dependence protocols) that will be of high priority for NIDA over the next few years and our CTPs are all well positioned to test and introduce medical interventions. The present proposal is contextualized by five years of CTN experience and by our assessment of the accomplishments of, and challenges facing, the CTN. Our overall thematic approach capitalizes on CTN and Node accomplishments to-date and addresses challenges for the future. We bring in new investigators and expertise, we describe an enhanced science-to-practice model for CTN studies, we expand relationships with state and local government agencies to enable this, and we propose a research concept that works within this framework. Themes include reaching out to primary-care providers, extending relevant outcomes, partnering with agencies that can share study costs and foster adoption, and addressing systems of reimbursement and organization of care. Our research concept builds on these themes to extend the reach of the CTN and to enhance the likelihood that CTN studies will have impact and lead to improved healthcare on a broader level.