South Texas Pediatric Minority Based CCOP

描述(由申请人提供)：南得克萨斯州以少数族裔为基础的社区临床肿瘤学计划(STP-MB-CCOP)的长期目标是降低居住在服务区的墨西哥裔美国人(MA；这里用作西班牙裔同义词)儿童和青少年的癌症发病率、发病率和死亡率。STP-MB-CCOP的四个具体目标是：1)为服务于南得克萨斯州地理区域的儿科肿瘤学提供者提供全面、综合的数据管理服务；2)为儿科肿瘤学家、数据管理和支持人员提供前往医疗服务不足地区的外联诊所的差旅支持；3)提供对服务地区墨西哥裔美国人口有文化敏感性的集中西班牙语翻译系统；4)制定与服务地区墨西哥裔美国人口相关的当地癌症控制试点举措。该研究计划涉及在圣安东尼奥设立一个临床研究办公室，负责协调组成机构的数据管理活动，包括收集和提交原始数据、IRB批准、西班牙语翻译、研究基地审计和样本收集。它将使用信息学数据交换和获取系统(IDEAS)，这是一个基于Web的系统，所有STP-MB-CCOP中心都可以访问该系统，无论其位置如何。将在边境县开展各级外联活动(对常驻儿科肿瘤学家的教育、数据管理支助和外联诊所)，使患有癌症的儿童和青少年能够参加临床试验。同意书和教育材料的集中西班牙语翻译将确保所有患者和家属都能收到以其母语提供的信息，从而对遵守治疗产生积极影响。STP-MB-CCOP正试图通过开发与墨西哥裔美国人有关的当地癌症控制倡议，并可推广到其他COG CCOP机构，来弥补儿科癌症控制和预防试验的匮乏。该方案有一个持续的评估方案，包括机构执行机构与其信用评级机构之间的每周会议，每月行政执行委员会的会议，以及由所有STP-MB-CCOP成员参加的季度会议，以审查财团的活动。

DESCRIPTION (provided by applicant): The long-term goal of the South Texas Pediatric Minority-Based Community Clinical Oncology Program (STP-MB-CCOP) is to reduce the incidence, morbidity and mortality of cancer among Mexican-American (MA; herein used synonymously with Hispanic) children and adolescents residing in the service area. The four specific aims of the STP-MB-CCOP are: 1) Provide comprehensive, integrated data management services accessible to pediatric oncology providers serving the geographic region known as South Texas; 2) Provide travel support for pediatric oncologists, data management and support personnel to outreach clinics within the medically under served areas; 3) Provide a centralized Spanish translation system culturally sensitive to the Mexican-American population in the service area; and 4) Develop local cancer control pilot initiatives relevant to the Mexican-American population in the service area. The research plan involves the operation of a Clinical Research Office in San Antonio that coordinates the data management activities of the component institutions, including primary data collection and submission, IRB approval, Spanish translation, research base audits and sample collection. It will use the Informatics Data Exchange and Acquisition System (IDEAS) a Web based system that can be accessed by all STP-MB-CCOP centers regardless of their location. Outreach activities at all level (education, data management support of resident pediatric oncologist and outreach clinics) will be provided in border counties to allow children and adolescents with cancer to have access to clinical trials. Centralized Spanish translation of consent forms and educational materials will assure that all patients and family receives information in their own language with a resulting positive impact on compliance with treatment. STP-MB-CCOP is attempting to remedy the paucity of pediatric cancer control and preventive trials by developing local cancer control initiatives pertinent to the Mexican-American population and expandable to other COG CCOP institutions. The program has an ongoing evaluation program involving weekly meetings between institution PIs and their CRAs, monthly meeting of the Administrative Executive Committee and quarterly meeting involving all STP-MB-CCOP members to review the consortium activities.