Drug Abuse and Other Deviant Adaptations to Stress

描述(由申请人提供)： 竞争延续高级科学家(K05)奖的候选人是董事教授、社会学特聘教授、马歇尔文科教授和德克萨斯农工大学社会偏离研究实验室主任。他的工作在一流的研究型大学、学院、系、实验室进行，具有丰富的学术和研究历史，有助于实现与研究、职业提升和指导活动有关的短期和长期职业目标。长期目标是将不断增加的专业知识应用于制定、测试和传播(通过出版和指导)药物滥用和其他变态适应模式的心理社会原因和后果的其他知情模式，以及这些关系的调节因素和共同前因。短期目标侧重于解释第二代(G2)小组在青春期早期(G2-T1)最初测试的先兆和药物滥用的后果以及其他异常模式的变化，并在K05奖的五年期间进行十年后(G2-T2)的随访。受试者是第一代(G1)小组的孩子，他们在7年级(G1-T1)、8年级(G1-T2)和9年级(G1-T3)期间接受了五次测试，作为20多岁的年轻人(G1-T4)，最近的一次测试是在第四个十年的后期(G1-T5)。药物(Ab)的使用和其他偏离模式及其在T2对G2的后果将被模拟为G1(T1-T5)和G2(T1)变量(个人访谈数据和社会环境情况普查指标)、缓和这些变量的影响以及共同的前因(来自相同的变量数组)的线性直接和间接(中介)影响的结果。这些模型由候选人的综合一般偏离理论提供信息，将使用结构方程/分层线性建模方法等方法进行估计。研究技能的提高将侧重于接触方法学发展、生命历程和代际影响文献中的新发现，以及与使用其他纵向数据集的研究人员合作。指导活动包括指导受雇于该项目的研究生和候选人讲授的研讨会，以及指导德克萨斯农工大学和德克萨斯大学的初级教员关于药物滥用和其他异常适应研究的实质和方法。

DESCRIPTION (provided by applicant): The candidate for a competing continuation Senior Scientist (K05) Award is Regents Professor, Distinguished Professor of Sociology, Marshall Professor of Liberal Arts, and Director for the Laboratory for Studies of Social Deviance at Texas A&M University. His work is carried out in a premier research university, college, department, laboratory characterized by a history of productive scholarship and research that facilitates achievement of both short and long-term career goals relating to research, career enhancement, and mentoring activities. The long-term goal is to apply ever-increasing expertise to the formulation, testing, and dissemination (by publication and instruction) of theotherically informed models of psychosocial causes and consequences of patterns of drug abuse and other deviant adaptations, and the moderators and common antecedents of these relations. The short-term goal focuses upon explaining changes in antecedents and consequences of drug abuse and other deviant patterns for a second generation (G2) panel initially testing during early adolescence (G2-T1) and followed up ten years later (G2-T2) during the five-year period of the K05 award. The subjects are the children of a first generation (G1) panel who were tested up to five times during the 7th (G1-T1), 8th (G1-T2), and 9th (G1-T3) grades, as young adults in their 20s (G1-T4), and most recently in the later part of the forth decade of life (G1-T5). Drug (ab)use and other deviant patterns and their consequences for G2 at T2 will be modeled as outcomes of linear direct and indirect (mediated) influences of G1 (T1- T5) and G2 (T1) variables (both personal interview data and census indictors of socio-environmental contexts); moderating influences of these same variables; and common antecedents (drawn from the same array of variables). The models, informed by the candidate's integrative general theory of deviance, will be estimated using structural equation/hierarchical linear modeling approaches among other methodologies. Enhancement of research skill will focus upon exposure to methodological developments, new findings in the life course and intergenerational influence literature, and collaboration with investigators using other longitudinal datasets. Mentoring activities include guidance of graduate students employed on the project and in a seminar taught by the candidate, and mentoring of junior faculty at Texas A&M and the University of Texas in the substance and method of research on drug abuse and other deviant adaptations.