Research Priorities in Ambulatory Management of Obstructive Sleep Apnea Workshop

该申请寻求部分财政支持，以举办一个关于研究优先事项的讲习班， 阻塞性睡眠呼吸暂停（OSA）的门诊治疗将于2007年10月15日至16日举行 在华盛顿据估计，中度至重度OSA影响4%的成年女性和9%的 成年男性在美国和这些人中的绝大多数是未确诊的。大 大量数据现在支持OSA是机动车事故的独立风险因素， 神经认知缺陷和心血管发病率和死亡率。大量证据还表明， 支持OSA的适当治疗可以降低这些后果的风险。然而 患者获得OSA的诊断和治疗存在一个主要问题， 需要在睡眠实验室进行昂贵且劳动密集型的多导睡眠图。 技术改进可能允许使用简化的便携式监护仪测试， OSA在不同的设置，包括无人值守的家庭录音。这种办法可能 降低成本，增加患者接受检测的机会，从而更早地识别疾病， 更快地开始治疗，从而减轻与阻塞性睡眠呼吸暂停相关的医疗保健负担。 对便携式监视器设备的临床应用的兴趣正在迅速增长，并且在一些实施例中， 在这种情况下，便携式监测已经成为OSA管理的主要方法。 尽管便携式显示器测试具有直观的吸引力，但验证数据仍然有限。最近的一 来自医学研究所的报告和来自AHRQ和专业人士的循证审查 社会发现主要缺陷，特别是关于无人看管的家庭便携式监视器 试验.计划中的OSA门诊管理研究优先事项研讨会是一个 直接回应这些报道。研讨会将汇集不同的利益相关者， 对便携式显示器测试的兴趣，以确定有关便携式显示器的研究重点 测试和制定关于这一关键领域的方法问题的具体建议 区我们认为这个研讨会是一个必要的？下一步呢？以确保 在这一重要领域的科学知识取得实质性进展。

The application seeks partial financial support for a workshop on research priorities in the ambulatory management of obstructive sleep apnea (OSA) to be held on October 15-16, 2007 in Washington, DC. Moderate to severe OSA is estimated to affect 4% of adult females and 9% of adult males in the US and a large majority of these individuals are undiagnosed. A large body of data now supports that OSA is an independent risk factor for motor vehicle accidents, neurocognitive deficits, and cardiovascular morbidity and mortality. Substantial evidence also supports that appropriate treatment of OSA reduces the risk of these consequences. However there is a major problem with patient access to diagnosis and treatment of OSA based on the need to perform costly and labor-intensive polysomnography in a sleep laboratory. Technological improvements may allow for the use of simplified portable monitor testing for OSA in diverse settings, including unattended home recordings. Such an approach might reduce cost and increase patient access to testing, leading to earlier recognition of disease and faster initiation of treatment, thereby reducing the health care burden associated with OSA. Interest in the clinical application of portable monitor devices is growing rapidly, and in some contexts, portable monitoring has become a mainstay approach to the management of OSA. Despite the intuitive appeal of portable monitor testing, validation data remain limited. A recent report from the Institute of Medicine and evidence based reviews from AHRQ and professional societies find major deficiencies particularly with regard to unattended home portable monitor testing. The planned workshop on research priorities in ambulatory management of OSA is a direct response to these reports. The workshop will bring together diverse stakeholders with interest in portable monitor testing to establish the research priorities regarding portable monitor testing and develop specific recommendations regarding methodological issues in this critical area. We submit that this workshop is an essential ?next step? to ensuring that there is substantive advancement of scientific knowledge in this important field.