RELAXATION AND HYPNOTIC TREATMENT OF DISABILITY-RELATED PAIN

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是检查两种放松和暗示程序对疼痛和疼痛干扰的即时和长期影响，相对于彼此和无治疗基线（4或8周，取决于患者的病情）在一组294名残疾人（多达134名脊髓损伤患者和160名飞行员：20例截肢，40例多发性硬化症，20例脑瘫，20例神经肌肉疾病，20例脊髓灰质炎后综合征，20例中风后疼痛患者，20例患有神经性疼痛），他们报告了令人烦恼的残疾相关疼痛。 SCI受试者将被随机分配到两种治疗条件之一：（1）“放松1”，这是一个放松训练条件，将包括一些常见的催眠成分（聚焦于视觉提示，放松的建议）以及感知镇痛的建议，或（2）“放松2”，其是将仅包括催眠的一个共同成分的放松训练条件（聚焦于视觉提示）加上用于减少肌肉紧张的生物反馈。 患有MS的初步研究参与者将被随机分配到两种治疗条件之一：（1）上述放松1条件，或（2）传统的放松训练条件，包括渐进式肌肉放松。 其余的试验参与者将在上述松弛1条件下入组。 主要结局变量（疼痛强度）和次要结局变量（疼痛干扰、医疗服务利用、抑郁和感知疼痛控制）均通过电话访谈进行评估。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to examine the immediate and long-term effects of two relaxation and suggestion procedures on pain and pain interference relative to each other and to a no-treatment baseline (four or eight weeks in length, depending on the patient's condition) in a group of 294 individuals with disability (up to 134 with spinal cord injury, and 160 pilots: 20 with amputation, 40 with multiple sclerosis, 20 with cerebral palsy, 20 with neuromuscular disease, 20 with post-polio syndrome, 20 post-stroke patients with pain, and 20 with neuropathic pain) who report bothersome disability-related pain. Study participants with SCI will be randomly assigned to one of two treatment conditions: (1) "Relaxation 1" which is a relaxation training condition that will include some components common to hypnosis (focusing on a visual cue, suggestions for relaxation) as well as suggestions for perceived analgesia or (2) "Relaxation 2" which is a relaxation training condition that will include only one component common to hypnosis (focusing on a visual cue) plus biofeedback for reduction of muscle tension. Pilot study participants with MS will be randomly assigned to one of two treatment conditions: (1) the Relaxation 1 condition described above, or (2) a traditional relaxation training condition that incorporates progressive muscle relaxation. The rest of the pilot participants will be enrolled in the Relaxation 1 condition described above. The primary outcome variable (pain intensity) and secondary outcome variables (pain interference, medical services utilization, depression, and perceived pain control) are all assessed via telephone interviews.