ANIMAL PHYSIOLOGY CORE
ANIMAL PHYSIOLOGY CORE
批准号:
7284677
负责人:
GEORGE L KING
金额:
$13.69万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-04-01 至 2012-03-31
关键词:
AnimalsBlood GlucoseBlood PressureBlood VesselsBody CompositionCategoriesDEXADiabetes MellitusEducational process of instructingEnergy MetabolismExerciseGlucose tolerance testHomeostasisHyperoxiaHypoxiaInsulinInvestigationMeasurementMonitorObesityOrganOxygenOxygen ConsumptionPhysiologicalPhysiologyPurposeResearch PersonnelRodentRodent ModelRunningServicesSystemTailTelemetryTestingTissuesblood glucose regulationdrinking behaviorfeedingin vivoinsulin toleranceintraperitoneal
中文摘要
Animal Physiology Core提供表征啮齿动物生理参数的服务
糖尿病、肥胖及其相关并发症的模型。这些服务包括
能量稳态的类别,运动期间的能量消耗,血管研究,缺血组织
研究和葡萄糖稳态。
能量稳态:进食/饮水行为、身体成分、耗氧量和活动
监测(CLAMS和DEXA)。
运动期间的能量消耗:啮齿动物跑步机跑步期间的氧气消耗(TM)。
血管研究:通过尾部血压袖带和遥测(BP)测量血压。
缺血组织研究:OxyCycler(OC)是一种控制环境氧气的体内系统
该浓度允许研究缺氧或高氧对各种器官和组织的影响。
葡萄糖稳态:监测血糖和胰岛素水平,腹膜内葡萄糖耐量试验
(GTT)胰岛素耐量试验(ITT)。根据研究者的要求提供,仅用于教学目的。
英文摘要
The Animal Physiology Core provides services to characterize the physiological parameters of rodent
models of diabetes, obesity and their associated complications. These services include measurements in the
categories of energy homeostasis, energy expenditure during exercise, vascular studies, ischemic tissue
studies and glucose homeostasis.
Energy Homeostasis: Feeding/drinking behavior, body composition, oxygen consumption and activity
monitoring (CLAMS and DEXA).
Energy Expenditure During Exercise: Oxygen consumption during rodent treadmill running (TM).
Vascular Studies: Blood pressure measurements by tail blood pressure cuffs and by telemetry (BP).
Ischemic Tissue Studies: The OxyCycler (OC) is an in vivo system that controls the ambient oxygen
concentration allowing investigation of the effects of hypoxia or hyperoxia on various organs and tissues.
Glucose Homeostasis: Monitoring of blood glucose and insulin levels, intraperitoneal glucose tolerance tests
(GTT), insulin tolerance tests (ITT). Available upon request by an investigator for teaching purposes only.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
A pilot clinical trial to assess feasibility, facilitators and barriers of continuous glucose monitoring in Asian Americans with type 2 diabetes
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批准号:10511276
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项目类别:
-
资助金额:$25.56万
-
财政年份:2022
-
负责人:GEORGE L KING
-
依托单位:
A pilot clinical trial to assess feasibility, facilitators and barriers of continuous glucose monitoring in Asian Americans with type 2 diabetes
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批准号:10709518
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项目类别:
-
资助金额:$21.31万
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财政年份:2022
-
负责人:GEORGE L KING
-
依托单位:
Characterization of cardiovascular diseases (CVD) in people with long duration Type 1 diabetes
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批准号:10543994
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项目类别:
-
资助金额:$77.58万
-
财政年份:2021
-
负责人:GEORGE L KING
-
依托单位:
Characterization of cardiovascular diseases (CVD) in people with long duration Type 1 diabetes
-
批准号:10372462
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项目类别:
-
资助金额:$85.09万
-
财政年份:2021
-
负责人:GEORGE L KING
-
依托单位:
Pyruvate kinase M2 levels and activation as protective factors for diabetic nephropathy
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批准号:9235747
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项目类别:
-
资助金额:$227.22万
-
财政年份:2016
-
负责人:GEORGE L KING
-
依托单位:
Characterization of Retinoid-Binding Protein 3 (RBP3): A Protective Factor Against Diabetic Retinopathy Identified in People with Extreme Diabetes Duration
-
批准号:10320034
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项目类别:
-
资助金额:$46.54万
-
财政年份:2016
-
负责人:GEORGE L KING
-
依托单位:
Characterization of Retinoid-Binding Protein 3 (RBP3): A Protective Factor Against Diabetic Retinopathy Identified in People with Extreme Diabetes Duration
-
批准号:10543746
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项目类别:
-
资助金额:$47.98万
-
财政年份:2016
-
负责人:GEORGE L KING
-
依托单位:
Identification of Retinoid-Binding Protein 3 (RBP3): A Protective Factor against Diabetic Retinopathy Using Retina from People with Extreme Duration of Diabetes
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批准号:9006846
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项目类别:
-
资助金额:$41.38万
-
财政年份:2016
-
负责人:GEORGE L KING
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依托单位:
Validation of Potential Protective Factors from Diabetic Complications
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批准号:8922182
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项目类别:
-
资助金额:$13.05万
-
财政年份:2011
-
负责人:GEORGE L KING
-
依托单位:
Validation of Potential Protective Factors from Diabetic Complications
-
批准号:8241364
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项目类别:
-
资助金额:$396.36万
-
财政年份:2011
-
负责人:GEORGE L KING
-
依托单位:
Protective Factors Against the Development of Microvascular Complications
-
批准号:8150968
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项目类别:
-
资助金额:$80.16万
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财政年份:2010
-
负责人:GEORGE L KING
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依托单位:
Protective Factors Against the Development of Microvascular Complications
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批准号:8478260
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项目类别:
-
资助金额:$23.54万
-
财政年份:2010
-
负责人:GEORGE L KING
-
依托单位:
Protective Factors Against the Development of Microvascular Complications
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批准号:8053117
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项目类别:
-
资助金额:$81.66万
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财政年份:2010
-
负责人:GEORGE L KING
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依托单位:
Cell Biology of Diabetic Microvascular Complications
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批准号:7388129
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项目类别:
-
资助金额:$40.67万
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财政年份:2007
-
负责人:GEORGE L KING
-
依托单位:
Cell Biology of Diabetic Microvascular Complications
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批准号:8047977
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项目类别:
-
资助金额:$39.44万
-
财政年份:2007
-
负责人:GEORGE L KING
-
依托单位:
INFLAMMATORY RESPONSE TO DIETS BETWEEN ASIANS AND CAUCASIANS
-
批准号:7606949
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项目类别:
-
资助金额:$0.47万
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财政年份:2007
-
负责人:GEORGE L KING
-
依托单位:
Cell Biology of Diabetic Microvascular Complications
-
批准号:7805460
-
项目类别:
-
资助金额:$41.09万
-
财政年份:2007
-
负责人:GEORGE L KING
-
依托单位:
Cell Biology of Diabetic Microvascular Complications
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批准号:7599524
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项目类别:
-
资助金额:$41.5万
-
财政年份:2007
-
负责人:GEORGE L KING
-
依托单位:
Cell Biology of Diabetic Microvascular Complications
-
批准号:7266763
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项目类别:
-
资助金额:$41.5万
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财政年份:2007
-
负责人:GEORGE L KING
-
依托单位:
PKC Activation and Cardiovascular Disease in Diabetes
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批准号:7107973
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项目类别:
-
资助金额:$40.52万
-
财政年份:2004
-
负责人:GEORGE L KING
-
依托单位:
海外基金