DYNAMIC PULMONARY IMAGING USING SPIRAL MR IMAGING

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。在啮齿动物的肺部进行真正的动态成像，使用超极化气体、氦和氙气进行螺旋成像。第一个目标是了解呼吸周期的动力学，并只执行质子扫描，以优化螺旋序列的成像和定时参数。下一个目标是扩展这些扫描，以展示执行动态惠普气体研究的能力。这些研究将影响该中心今后的工作。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Perform true dynamic imaging in rodent lungs using spiral imaging using hyperpolarized gases, Helium and Xenon. The first goal is to understand the dynamics of the respiratory cycle, and perform only proton scans to optimize the imaging and timing parameters of the spiral sequence. The next goal is to extend these scans to demonstrate the capability of performing dynamic HP gas studies. These studies will impact future work in the Center.