GUIDED IMAGERY STRESS REDUCTION INTERVENTION FOR OBESE LATINO ADOLESCENTS:

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。这项试点和可行性研究的总体目标是：1)制定一项为期12周的、基于理论的、引导图像的生活方式干预，以减少超重拉美裔青少年2型糖尿病和心血管疾病的危险因素；2)测试意象干预前4周对研究人群压力、应激激素（皮质醇）水平和糖尿病危险因素的影响。焦点小组定性方法将用于制定引导意象干预，之后将12名受试者随机分为非干预对照组和每周接受4次减压引导意象治疗的研究组。干预前和干预后的应激、唾液和尿液游离皮质醇、葡萄糖耐量、胰岛素敏感性和分泌指数、身体成分和血脂的评估将在研究组和对照组之间进行比较。如果引导图像被证明在减少压力、压力激素水平和糖尿病风险因素方面是有效的，这将代表一个重要的、创新的行为干预方法，以解决超重拉丁裔青少年日益严重的肥胖和2型糖尿病问题。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall aim of this pilot and feasibility study is to 1)develop a 12-week, theory-based, guided imagery lifestyle intervention to reduce risk factors for type 2 diabetes and cardiovascular disease in overweight Latino adolescents; and 2) to test the effects of the first 4 weeks of the imagery intervention on stress, stress hormone (cortisol) levels, and diabetes risk factors in the study population. Focus group qualitative methodologies will be used to develop the guided imagery intervention, after which 12 subjects will be randomized into a non-intervention control group, and a study group that will receive 4 weekly stress-reduction guided imagery sessions. Pre- and post-intervention assessments of stress, salivary and urinary free cortisol, glucose tolerance, indices of insulin sensitivity and secretion, body composition, and plasma lipids will be compared between study and control groups. If guided imagery is shown to be effective at reducing stress, stress hormone levels, and diabetes risk factors, this would represent a significant, and innovative, behavioral intervention approach to the increasing problem of obesity and type 2 diabetes in overweight Latino adolescents.