AN OBSERVATIONAL STUDY OF THE RATE OF OPPORTUNISTIC INFECTION EVENTS IN HIV

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定为研究者机构。一项旨在确定中止PCP和MAC预防方案对严重细菌感染和其他机会性感染（HIV）发生率的影响和安全性的观察性研究。此外，还将接种甲型肝炎疫苗，以测量对新抗原的应答。将对2至21岁的患者进行观察，直至最后一例入组患者完成104周观察。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. An observational study to determine the impact and safety of discontinuing PCP and MAC prophylaxis regimens in relation to the incidence of serious bacterial infections and other opportunistic infections (HIV). Additionally, there will be an administration of Hepatitis A vaccine to measure response to neoantigen. Patients, ages 2 to 21 years, will be observed until the last patient enrolled has completed 104 weeks of observation.