EFFECTS OF DASH-SODIUM DIET ON SYMPATHETIC NERVOUS SYSTEM ACTIVATION IN

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定为研究者机构。饮食方法停止高血压（DAS）饮食已被证明可以显着降低血压（BP）的参与者与正常和轻度升高的血压。然而，目前尚不清楚DASH饮食是否可以成为慢性肾脏疾病患者高血压管理的重要工具。本研究利用24小时动态血压监测和显微神经造影技术，以确定DASH低钠饮食是否能有效降低轻中度慢性肾脏疾病患者的血压，并确定DASH低钠饮食对交感神经系统和压力感受器功能的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Dietary Approaches to Stop Hypertension (DAS) diet has been shown to significantly lower blood pressure (BP) in participants with both normal and mildly elevated blood pressure. However, it is unclear whether DASH diet can be an important adjunctive tool in management of hypertension in people with chronic kidney diseases. Current study utilizes the techniques of 24-hr ambulatory BP monitoring and microneurography to determine if DASH low-sodium diet is effective in blood pressure reduction in patients with mild to moderate chronic kidney disease, and to determine the impact of DASH-low sodium diet on sympathetic nervous system and on baroreceptor function.