OPERATIONAL STATUS OF THE 24-ID-C BEAMLINE

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。去年在24-ID-C插入光束线上的活动主要集中在：1。晶体学调试：测试表征良好的晶体（溶菌酶，thaumatin等），以微调光束线并对其进行优化，以获得最高质量的晶体学数据。2. 通过增加新的软件和硬件功能，进一步增强了光束线光学和控制组件。3. 在晶体学调试期间，对光束线的诊断测试证明了24-ID-C光束线能够从低r合并因子（1.4¿分辨率~0.04）的衍射晶体中产生高质量的晶体学数据。其他测试表明，即使曝光时间小至100毫秒，数据质量也不会下降。在7000-9000 eV范围内的低能数据收集也显示了利用硫原子的弱异常信号求解结构的可行性，重申了从24-ID-C束流线获得的高质量数据。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The last year's activities at the 24-ID-C insertion beamline have focused upon: 1. Crystallographic commissioning ¿ testing well characterized crystals (lysozyme, thaumatin, etc.) to fine tune the beam line and to optimize it to get the highest quality crystallographic data. 2. Further enhancement of the beamline optical and control components with the addition of new software and hardware capabilities. 3. Transition to full-time user data collection Diagnostic testing of the beamline during crystallographic commissioning has proven the capability of the 24-ID-C beam line in producing high quality crystallographic data from well diffracting crystals with low R-merge factor (~0.04 for 1.4 ¿ resolution). Additional tests have demonstrated no deterioration in data quality for exposure times as small as 100 msec. Low-energy data collection in the range of 7000-9000 eV has also shown the feasibility of solving structures by employing weak anomalous signal from sulphur atoms, reiterating the high quality of data obtainable from the 24-ID-C beam line.