ANGIOGENIC ENDOTHELIAL CELL DETECTION IN PERIPHERAL CIRCULATION IN METASTATIC DS

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这是一项自愿的研究，目的是看看简单的血液测试是否可以检测到血液中是否存在只可能由癌细胞血管产生的基因。大约60名受试者将被纳入这项研究。将有三组受试者。将有20名受试者组成，其中包括20名健康人，20名患有癌症从身体一个区域扩散到另一个区域的受试者，以及20名受试者将接受名为Octrether的研究药物的治疗。前两组受试者一次献血约5毫升。接受奥曲通治疗的受试者在治疗前献血约5毫升，每次奥曲塞治疗后献血一次(最多3茶匙)。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a voluntary research study to see if a simple blood test can detect the presence of a gene in the blood which may be produced only by cancer cell blood vessels. Approximately 60 subjects will be enrolled into this study. There will be three groups of subjects. There will be 20 subjects that will consist of healthy individuals, 20 subjects with cancer that has spread from one area to another in the body and 20 subjects will be receiving treatment with a study drug called Octreother. Subjects in the first two groups will donate approximately 5cc of blood on one occasion. Subjects undergoing treatment with Octreother will donate approximately 5cc of blood prior to treatment and one after each treatment with Octreother (maximum three teaspoons).