SAGITTAL SYNOSTOSIS: 3D PHOTOGRAPHY PROJECT

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定为研究者机构。这项试点研究正在进行，以确定最好的方法来表征头部形状的差异，观察到的个人与矢状缝早闭及其亲属。本研究中收集和分析的数据将被用作更大研究计划的初步数据，以确定矢状骨缝早闭的原因。骨缝早闭导致舟状头畸形，一种狭长的头部形状，前额突出，枕骨狭窄隆起。在少数家庭中，其他亲属被诊断为矢状骨缝早闭。一些家族报告家族成员有长窄头或大额头，但没有被诊断为矢状骨结合。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This pilot study is being done to determine the best method of characterizing head shape differences observed in individuals with sagittal synostosis and their relatives. Data collected and analyzed in this study will be used as preliminary data in a larger research proposal to identify causes of sagittal synostosis. Sagittal synostosis results in scaphocephaly, a long narrow head shape with a prominent forehead and narrow bulging occiput. In a few families, additional relatives have been diagnosed with sagittal synostosis. Some families have reported family members with long narrow heads or large foreheads, who have not been diagnosed with sagittal synostosis.