PACTG P1042S: CORRELATES OF MEDICATION ADHERENCE IN CHILDREN & ADOLESCENTS W/HI

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。PACTG 1042 s是一项横断面研究，将认知、行为和心理社会功能与围产期获得性HIV感染儿童和青少年抗逆转录病毒药物治疗方案的责任程度和依从性相关联。它还将把认知、行为和心理社会功能与病毒抑制和免疫状态的测量相关联，并比较自我报告和药丸计数的依从性测量。200例可评估的围产期获得性HIV-1感染的8至<19岁儿童和青少年，入组PACTG 219 C并进行积极随访，将被分层为两组; < 12岁和≥ 12岁。每例受试者的研究将持续48个月。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. PACTG 1042s is a cross-sectional study that will correlate cognitive, behavioral, and psychosocial functioning with the degree of responsibility for and adherence to antiretroviral medication regimens in children and adolescents with perinatally acquired HIV infection. It will also correlate cognitive, behavioral and psychosocial functioning with measures of virologic suppression and immunological status, and compare self-report and pill count measures of adherence. 200 evaluable children and adolescents with perinatally acquired HIV-1 infection 8 to <19 years of age, who are enrolled and in active follow-up in PACTG 219C, will be stratified into two groups; < 12 years of age and = 12 years of age. The study will last 48 months for each subject.