FAMILY STUDIES

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究的目的是探讨糖尿病和心血管疾病（CVD）风险的决定因素在受影响的先证者及其家庭成员。我们认为，目前最关键的研究领域是揭示糖尿病和肥胖的遗传易感性的作用，以及它与不断变化的流行病学行为风险因素的相互作用。主要数据收集将在先证者家中完成，并通过CRC在CORE实验室进行处理。此外，CRC将用于那些家庭想要参与但不希望研究人员来他们家的情况（第1级）。CRC还将用于更详细的检查，其中一部分参与者之前在他们的家中或CRC（2级）见过。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to investigate the determinants of diabetes and cardiovascular disease (CVD) risk in affected probands and their family members. We believe that the most critical area of research at this point in time is to unravel the role of genetic susceptibility to diabetes and obesity, and its interaction with the changing epidemiology of behavioral risk factors. The primary data collection data will be done in the proband's home and processed in the CORE laboratory through the CRC. Also, the CRC will be used for those instances when a family wants to participate but does not want to have the research staff come to their home (level 1). The CRC will also be used for a more detailed exam with a sub-set of participants who were seen previously in their home or the CRC (level 2).