CHILDREN'S RECALL AND RECOGNITION MEMORY FOR TEMPORAL SEQUENCES

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。再现和回忆过去是大多数成年人认为理所当然的基本能力。传统上，人们认为各种各样的缺陷使3岁以下的儿童无法分享这种精神生活的特征。与这些假设相反，越来越多的证据表明，支持长期外显记忆的神经基质在生命第一年的下半年开始合并。这一时期长期记忆的变异性以及大脑与长期外显记忆的行为指标之间的关系的研究结果与这一观点一致。这些研究结果表明，在新记忆的编码和巩固方面的差异，在记忆痕迹对遗忘的脆弱性方面的差异，或者两者兼而有之，是第一年下半年长期外显记忆的个体差异的来源。在两个实验中，我们结合了助记性能的行为和电生理指标来识别个体差异的来源。因此，预期正在进行的研究将提供有关发展变化产生因素的资料。GCRC将在安排参与者、为婴儿护理提供空间以及为ERP测试会议的管理和协助提供技术人员方面成为该提案的组成部分。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Representing and recalling the past are fundamental capacities that most adults take for granted. Traditionally, it was thought that a variety of deficits rendered children under 3 year of age incapable of sharing this feature of mental life. Contrary to these assumptions there is increasing evidence that the neural substrate that supports explicit memory over the long-term begins to coalesce in the second half of the first year of life. Findings of variability in long-term memory in this period and of relations between brain and behavioral indices of long-term explicit memory are consistent with this suggestion. The findings converge to suggest that differences in the encoding and consolidation of new memories, in the vulnerability of memory traces to forgetting, or both, are the sources for individual differences in long-term explicit memory in the latter part of the first year. In two experiments we combine behavioral and electrophysiological indices of mnemonic performance to identify the source or sources of individual variability. The on-going research thus is expected to inform as to the generators of developmental change. The GCRC will be integral to this proposal in scheduling or participants, supplying space in the infancy care, and providing a technician for administration and assistance with the ERP testing sessions.