IMPROVING ORTHOSTATIC TOL IN WOMEN: CONTROL OF SPLANCHNIC & CUTANEOUS VAS CAPAC

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项建议寻求利用药物对策来提高女性的立位耐受性。我们推测，在头高位倾斜(HUT)前输注奥曲肽将减少内脏血流量，导致血液重新分配到身体的其他区域，从而提高立位耐力。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This proposal seeks to utilize pharmacological countermeasures to improve orthostatic tolerance in women. We postulate that an infusion of octreotide prior to head-up tilt (HUT) will decrease splanchnic blood flow, causing a redistribution of blood to other regions of the body and thus will improve orthostatic tolerance.