AR CAREER DEVELOPMENT COBRE: EXPERIMENTAL CORE

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。实验核心现在有三个核心设施。电生理学核心设施承担了与人类中潜伏期听觉诱发反应相关的研究，如唤醒（注意前）测量，精神运动警觉性任务（PVT）反应时间测试中表现出的注意测量，操作性测试电池（OTB）表现出的认知功能，以及使用近红外光谱（NIRS）测量的相对额叶血流量。图像分析核心是在该奖项的第一年开发的，包括一个带有荧光和图像分析软件的共聚焦显微镜，以及用于在体外记录装置中可视化电压依赖性和钙染料的高速摄像机。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Experimental Core now has three Core Facilities. The Electrophysiology Core Facility undertakes studies related to human midlatency uditory evoked responses as arousal (pre-attentional) measures, attentional measures as exhibited by performance of a Psychomotor Vigilance Task (PVT) reaction time test, cognitive functions as exhibited in the performance of an Operant Test Battery (OTB), and relative frontal lobe blood flow as measured using Near Infrared Spectroscopy (NIRS). The Image Analysis Core was developed during Year 1 of the award and consists of a confocal microscope with fluorescence and image analysis software, along with a high speed camera for visualizing voltage-dependent and calcium dyes in the in vitro recording rig.