AR CAREER DEVELOPMENT COBRE: EXPERIMENTAL CORE

这个子项目是利用资源的许多研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 子项目的主要研究者可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 实验核心现在有五个核心设施。 人体电生理学核心设施进行了与人类中潜伏期诱发反应相关的研究，如唤醒（前注意力）测量，注意力测量，如通过执行心理警戒任务（PVT）反应时间测试所表现出的，认知功能，如在操作测试组合（OTB）中表现出的，以及使用近红外光谱（NIRS）测量的相对额叶血流。 图像分析核心是在该奖项的第一年开发的，包括一个带有荧光和图像分析软件的共聚焦显微镜，沿着一个高速相机，用于在体外记录装置中可视化电压依赖性和钙染料。动物电生理学核心有P13电位和大鼠TMS设施。 Molecular Core具有bRT-PCR、Luminex和其他检测。 TMS核心有设施的TMS在人类的一些疾病。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Experimental Core now has five Core Facilities. The Human Electrophysiology Core Facility undertakes studies related to human midlatency uditory evoked responses as arousal (pre-attentional) measures, attentional measures as exhibited by performance of a Psychomotor Vigilance Task (PVT) reaction time test, cognitive functions as exhibited in the performance of an Operant Test Battery (OTB), and relative frontal lobe blood flow as measured using Near Infrared Spectroscopy (NIRS). The Image Analysis Core was developed during Year 1 of the award and consists of a confocal microscope with fluorescence and image analysis software, along with a high speed camera for visualizing voltage-dependent and calcium dyes in the in vitro recording rig. The Animal Electrophysiology Core has P13 potential and TMS facilities for rats. The Molecular Core has bRT-PCR, Luminex and other assays. The TMS Core has facilities for TMS in humans for a number of disorders.