Spatio-temporal modeling network on plant systems (STEMN)

虽然了解细胞在生物体内和跨物种中普遍存在的各个方面是至关重要的，但对于高等生物体来说，在发育过程中出现的细胞之间的时空差异和对环境的反应是特别重要的。人与猿的区别在于完整的系统，同样，高等植物与藻类的区别也在于细胞类型及其整合的差异。关于基因表达模式、调控系统、机械特性等时空决定因素的研究活动越来越多，这些因素综合起来导致生长和发育，而且越来越需要建立观察的数学模型，更重要的是，建立潜在的机制。这些可能非常复杂，因为必须了解更改之间的关系。换句话说，尽管可以孤立地研究各个组成部分，但只有将它们作为一个整体来对待，才能获得充分的理解。这需要简明的数学模型，通常要转化为可计算的模型。虽然这项工作的重点是植物，但它将具有普遍的应用价值。该网络的最初目标是促进数学思想、方法的快速传播和潜在问题的阐明，一个遥远的目标是创造一个虚拟植物。

Whilst it is essential to understand aspects of cells that are common within organisms and across species it is the spatio-temporal differences between cells that arise during development and responses to the environment that are of particular importance to higher organisms. What distinguishes man from the ape is the integrated system, likewise it is the differences between cell types and their integration that distinguishes higher plants from algae. There is increasing research activity on the spatio-temporal determinants of gene expression patterns, regulatory control systems, mechanical properties, etc. that integrate to lead to growth and development and there is an increasing need to create mathematical, models of the observations and, more importantly, the underlying mechanisms. These can be quite complex because the relationships between the changes have to be understood in relation to each other. In other words, although components can be studied in isolation a full understanding is only obtained when they are treated as an integrated whole. This requires concise mathematical models that are usually translated into computable models. Although focussed on plants, the work will have general application. The initial goal of the network is to catalyse the rapid distribution of mathematical ideas, methods and the articulation of potential problems, a distant goal is the creation of a Virtual Plant.