PREPARATION, DERIVATIZATION &: NANOSTRUCTURED MATERIALS

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。两亲嵌段共聚物的自组装和共价稳定是制备结构、组成和尺寸明确的坚固纳米结构材料的一种方法，这种材料是为特定材料特性而设计的，并表现出选择性的生物相互作用。MALDI-TOF已成为表征两亲性嵌段共聚物的重要表征工具。质谱分析在表征用于修饰纳米结构的分子成分（如抗生素、肽、糖等）方面也发挥了重要作用。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The self-assembly and covalent stabilization of amphiphilic block copolymers is being developed as a methodology for the preparation of robust nanostructured materials of well-defined structure, composition, and size, which are designed for specific materials properties and to exhibit selective biological interactions. MALDI-TOF has been a critical characterization tool for the characterization of the amphiphilic block copolymers. Mass spectrometric analysis has also played a significant role in the characterization of molecular components, e.g. antibiotics, peptides, sugars, etc., used to surface decorate the nanostructures.