AMPHILIC HYPERBRANCHED LINEAR HYBRID STAR POLYMERS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。带有五氟苯基链端基的超支化含氟聚合物与氨基封端的聚环氧乙烷发生亲核芳族取代反应，生成具有两亲特性的杂化超支化-线性星星聚合物。这些材料对于它们的单分子胶束特性是重要的，并且它们还充当用于产生呈现纳米级分辨的表面形貌和形态的最小粘附性膜、涂层和膜的前体。质谱法已被应用于超支化含氟聚合物、线性聚环氧乙烷的表征，特别是通过允许测定星星臂的数目和臂分布，预计质谱法对于星星聚合物的表征是相当有价值的。这些数据难以通过其他手段（例如，典型的分子量分析）确定，因为两亲性行为和球形形状。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hyperbranched fluoropolymers bearing pentafluorophenyl chain end groups undergo nucleophilic aromatic substitution reactions with amino-terminated poly(ethylene oxide)s to produce hybrid hyperbranched-linear star polymers of amphiphilic character. These materials are important for their unimolecular micelle character and they also serve as precursors for the generation of minimally-adhesive films, coatings, and membranes that present nanoscopically-resolved surface topographies and morphologies. Mass spectrometry has been applied toward the characterization of the hyperbranched fluoropolymers, linear poly(ethylene oxide)s and it is expected to be quite valuable for the characterization of the star polymers, in particular, by allowing for determination of the number of star arms and the arm distribution. These data are difficult to determine by other means, for example, typical molecular weight analyses, because of the amphiphilic behavior and the globular s hap e.