A Miniature Monitor for Time-Resolved Airborne Particle Chemistry

描述（由申请人提供）将开发一种微型电池供电的监测器，用于测量对人体暴露很重要的PM2.5气溶胶化学成分的小时浓度。该方法利用层流、水冷凝方法来提供环境颗粒的浓缩的、“准备分析”的存款。许多沉积物将被包含在单个收集晶片上，该晶片被设计用于通过普通液相色谱方法进行自动分析。目标是对环境颗粒物的单个成分进行大范围、廉价的时间分辨监测，以评估个人暴露情况。公共卫生相关性：建议开发一种紧凑的电池供电监测器，以提供对PM2.5中许多有毒化学成分的个人暴露的时间分辨测量。短期接触高浓度的放射性物质对于了解接触对呼吸和心血管健康的影响可能很重要。这项研究提高了时间分辨率和可以在个人监测研究中测量的化学成分的范围。

DESCRIPTION (provided by applicant A miniature, battery-powered monitor will be developed for measurement of hourly concentrations of chemical constituents of PM2.5 aerosols that are important to human exposure. The method utilizes a laminar-flow, water condensation method to provide a concentrated, "ready-to-analyze" deposit of ambient particles. Many deposits will be contained on a single collection wafer designed for automatic analysis by common liquid chromatographic methods. The objective is wide-scale, inexpensive time-resolved monitoring of individual constituents of ambient particulate matter for personal exposures assessment. PUBLIC HEALTH RELEVANCE: Proposed is the development of a compact, battery powered monitor to provide time-resolved measurements of personal exposures to many of the toxic chemical components of PM2.5. Short- term exposures to high levels may be important for understand the respiratory and cardiovascular health effects of exposure. This research improves the time-resolution and the range of chemical components that can be measured in personal monitoring studies.