Application to host a visiting researcher to collaborate on biocompatible adsorbents for blood purification

该研究提案的主要目的是开发用于血液净化的有效且生物相容的低成本吸附剂。深入了解碳微观结构对中分子（尿毒症毒素）去除的影响以及碳表面化学对较大血液蛋白相互作用的影响（影响材料的生物相容性）之间的关系，将导致开发有效且更经济的血液净化吸附剂。该研究旨在最大限度地减少碳吸附剂表面与血液接触时的任何不良炎症反应。这不仅将带来新的知识，而且还将带来新的和更好的治疗方法，使患有肾和肝衰竭、败血症和其他临床病症的患者直接受益。

The principal aim of the research proposal is to develop effective and biocompatible low cost adsorbents for blood purification. Insight into the relationship between the carbon microstructure on the removal of middle molecules (uraemic toxins) and the influence of the carbon's surface chemistry on the interaction of larger blood proteins (influencing the material's biocompatibility) will result in the development of effective and more economic adsorbents for blood purification. The research seeks to minimize any adverse inflammatory responses upon contact between the carbon adsorbent surface and blood. This will lead not only to new knowledge but also to new and better treatment therapies of direct benefit to patients suffering from renal and liver failure, sepsis and other clinical conditions.