TRANSFUSION MEDICINE/HEMOSTASIS TRAIL SITE AT PSBC

描述（由申请人提供） 我们是全美17个参与NHLBI赞助的输血医学/止血临床试验网络的试验中心之一。Slichter博士担任血小板剂量试验（PLADO）的首席研究员，这是该网络发起的第一项研究。她曾担任血小板小组委员会主席或联合主席，是PLADO协议委员会主席，并参加财务和出版物常设委员会。在本次更新期间，她将参与制定评估血沉棕黄层血小板的方案。Price博士是粒细胞输注试验的首席研究员，并主持粒细胞小组委员会。这项审判定于2007年开始。他还参加了TTP小组委员会。Gernsheimer博士曾担任ITP小组委员会主席，最近成为血小板小组委员会主席，并参加HITT小组委员会。她还将参加新成立的外科出血小组委员会。她是PSBC船舶研究的首席研究员。她已被指定为主要研究者，以开发试验，以评估ε-氨基-辛酸（EACA）作为血小板输注治疗的辅助剂。（更新申请建议方案#2）。汤普森博士参加了血友病小组委员会。在已启动、正在筹备或拟议的网络试验中，PSBC正在参与或计划参与PLADO、SHIP、粒细胞、星星、HOT、血小板生成素治疗儿童ITP、FAT和EACA以及血小板输注试验。我们仍在与儿童医院的血友病专家（Dana马修斯博士）合作，以确定她是否愿意招募患者参加RICH试验。 Puget Sound血液中心评论

DESCRIPTION (provided by applicant) We are one of 17 trial sites across the U.S. that are participating in the NHLBI-sponsored Transfusion Medicine/Hemostasis Clinical Trials Network. Dr. Slichter serves as the lead investigator for the Platelet Dose Trial (PLADO) that was the first study initiated by the Network. She has been Chairman or Co- Chairman of the Platelet Subcommittee, is the Chair of the PLADO Protocol Committee, and participates in the Finance and Publications standing committees. During this renewal, she will participate in the development of a protocol to evaluate buffy-coat platelets. Dr. Price is the lead investigator for the Granulocyte Transfusion Trial and chairs the Granulocyte Sub- committee. This trial is scheduled to be initiated in 2007. He also participates in the TTP Subcommittee. Dr. Gernsheimer has been a Chairman of the ITP Subcommittee, has recently become the Chair of the Platelet Subcommittee, and participates in the HITT Subcommittee. She will also participate in the newly- established Surgical Bleeding Subcommittee. She is PSBC's lead investigator for the SHIP Study. She has been designated as the Principal Investigator to develop the trial to evaluate epsilon-amino-caprioc acid (EACA) as an adjuvent to platelet transfusion therapy. (Renewal application proposed protocol #2). Dr. Thompson participates in the Hemophilia Subcommittee. Of the initiated, in the pipeline, or proposed Network trials, PSBC is participating or plans to participate in the PLADO, SHIP, Granulocyte, STAR, HOT, Thrombopoietin in Childhood ITP, FAT and EACA and platelet transfusion trials. We are still working with the Hemophilia specialist (Dr. Dana Matthews) at our Childrens Hospital to determine if she is willing to enroll patients in the RICH trial. PUGET SOUND BLOOD CENTER CRITIQUES