Advancing Biomedical Research with FTIR Spectroscopic Imaging

陈博士此次奖学金的研究计划将侧重于傅里叶变换红外(FTIR)光谱成像在生物医学样本研究中的应用。这些组织包括胃肠道(GI)组织、皮肤、骨骼和其他生物医学组织。该奖学金将包括伦敦帝国理工学院和罗格斯大学的研究，前者是FTIR成像应用的领先中心之一，后者是使用FTIR成像分析生物医学样品的领先中心之一。工作方案还将包括与物理和医学科学家、生物工程师、药剂师和在医院工作的医生进行互动。与目前使用的许多其他成像方法相比，FTIR光谱成像具有许多优点。这种方法的主要优点是化学特异性，但空间分辨率和采集时间也足以用于非均质生物医学样品的研究。该奖学金将允许陈博士开发将FTIR成像应用于生物医学样本的基本方法；研究将包括FTIR成像应用于生物医学组织的适用性测试和灵敏度水平的探索。

The research programme for this Fellowship for Dr. Chan will focus on applications of Fourier Transformed Infrared (FTIR) spectroscopic imaging to study biomedical samples. These will include gastrointestinal (GI) tissue, skin, bone and other biomedical tissues. The Fellowship will include research at Imperial College London, one of the leading centres in applications of FTIR imaging, and Rutgers University, one of the leading centres on the use of FTIR imaging for analysis of biomedical samples. The programme of work will also include interaction with physical and medical scientists, bioengineers, pharmacists and medical doctors working in hospitals. The FTIR spectroscopic imaging has a number of advantages compared with many other currently used imaging methods. The chemical specificity is the main advantage of this method but spatial resolution and acquisition time is also sufficient for studies of heterogeneous biomedical samples. The Fellowship will allow Dr. Chan to develop underlining methodology for applications of FTIR imaging to biomedical samples; the studies will include tests of applicability and exploring of sensitivity levels in applications of FTIR imaging to biomedical tissues.