Enzymes, Coenzyme Metabolic Pathways Gordon Research Conference

描述（由申请人提供）：根据此提案，我们寻求2008年和2009年“酶、辅酶和代谢途径”戈登研究会议的部分支持，该会议定于2008年7月13日至18日和2009年7月12日至17日在缅因州比德福德的新英格兰大学举行。本次会议的广泛和长期目标是促进对生物过程的分子水平理解，包括生化途径及其相关催化剂。我们的具体目标是呈现一个36位演讲者的计划，其中8位从海报摘要中选择，描述天然产物生物合成的最新进展，代谢途径的新方法，运动中的蛋白质，药物酶学进展，核酸酶学，信号转导，调节蛋白水解和酶学前沿。下午的海报会议为所有与会者提供了一个展示他们工作的场所，为初级调查员提供了与现场高级调查员互动的机会。这一提议的意义在于，酶GRC作为研究人员研究生化反应分子机制的试金石。这种应用与健康的关系源于这样一个事实，即疾病过程的分子描述对于化疗的设计是不可或缺的。

DESCRIPTION (provided by applicant): With this proposal, we seek partial support for the 2008 and 2009 Gordon Research Conferences on "Enzymes, Coenzymes and Metabolic Pathways", which are scheduled for July 13-18, 2008, and July 12-17, 2009, at the University of New England in Biddeford, Maine. The broad and long-term goal of this conference is to foster a molecular level understanding of biological processes, including biochemical pathways and their associated catalysts. Our specific aim is to present a program of 36 speakers, 8 chosen from poster abstracts, describing recent advances in Natural Product Biosynthesis, New Approaches to Metabolic Pathways, Proteins on the Move, Advances in Medicinal Enzymology, Nucleic Acid Enzymology, Signal Transduction, Regulated Proteolysis and Frontiers in Enzymology. Afternoon poster sessions provide a venue for all attendees to present their work, providing junior investigators the opportunity to interact with senior investigators in the field. The significance of this proposal is that the Enzymes GRC serves as the touchstone for the community of researchers investigating the molecular mechanisms of biochemical reactions. The health-relatedness of this application derives from the fact that a molecular description of disease processes is indispensable for the design of chemotherapy.