Generation of singlet oxygen mediated by silicon nanoassemblies for novel organic catalytic reactions

该拟议项目属于可持续化学技术领域，最终目标是开发一种新型通用方法来实现清洁有机合成。的方法，利用单线态氧的非对映体和对映体选择性反应的反应性，将被开发。所提出的方法是，独特的，基于最近发现的高效生成1O2，介导的硅纳米晶体组件，和新的反应工程概念的多功能结构化反应器与嵌入式发光二极管之间的协同作用。该提案确定了在清洁有机催化中采用过程强化（通过非热活化和热活化，即增强质量和热传递）和功能性纳米材料的新概念的巨大潜力。最重要的是，该提案涉及清洁有机合成和分子非热活化领域的发展不足。

The proposed project is in the area of sustainable chemical technology and is ultimately aimed at developing a novel generic approach towards clean organic synthesis. The methodology, exploiting reactivity of singlet oxygen in diastereo- and enantioselective reactions, will be developed. The proposed methodology is, uniquely, based on the synergy between recently discovered highly effective generation of 1O2, mediated by silicon nanocrystals assemblies, and the novel reaction engineering concept of multifunctional structured reactors with imbedded light-emitting diodes. The proposal identifies the significant potential of adopting new concepts of process intensification (via non-thermal activation and miniaturisation, i.e. enhanced mass and heat transfer) and functional nanomaterials in clean organic catalysis. Most significantly, the proposal addresses the underdevelopments in the areas of clean organic synthesis and non-thermal activation of molecules.